Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib MZ7-mel 1.0000
uM
 72
hr
 1040 308 0.3049 0.3076 0.2962 0.2389 3
Selumetinib MZ7-mel 1.0000
uM
 72
hr
 1180 307 0.3637 0.3076 0.2602 0.2389 4
Selumetinib MZ7-mel 3.1600
uM
 24
hr
 1050 40 0.7652 0.8087 0.0381 0.0358 1
Selumetinib MZ7-mel 3.1600
uM
 24
hr
 1157 34 0.8508 0.8087 0.0294 0.0358 2
Selumetinib MZ7-mel 3.1600
uM
 24
hr
 1179 34 0.8674 0.8087 0.0288 0.0358 3
Selumetinib MZ7-mel 3.1600
uM
 24
hr
 1041 49 0.7515 0.8087 0.0471 0.0358 4
Selumetinib MZ7-mel 3.1600
uM
 48
hr
 1830 122 0.5288 0.4920 0.0667 0.0696 1
Selumetinib MZ7-mel 3.1600
uM
 48
hr
 1877 109 0.5474 0.4920 0.0581 0.0696 2
Selumetinib MZ7-mel 3.1600
uM
 48
hr
 1577 120 0.4511 0.4920 0.0761 0.0696 3
Selumetinib MZ7-mel 3.1600
uM
 48
hr
 1544 120 0.4409 0.4920 0.0777 0.0696 4
Selumetinib MZ7-mel 3.1600
uM
 72
hr
 1033 272 0.3170 0.3101 0.2633 0.3136 1
Selumetinib MZ7-mel 3.1600
uM
 72
hr
 1227 422 0.3353 0.3101 0.3439 0.3136 2
Selumetinib MZ7-mel 3.1600
uM
 72
hr
 918 284 0.2641 0.3101 0.3094 0.3136 3
Selumetinib MZ7-mel 3.1600
uM
 72
hr
 1175 397 0.3241 0.3101 0.3379 0.3136 4
Vemurafenib MZ7-mel 0.0032
uM
 24
hr
 1108 14 0.8288 0.9820 0.0126 0.0137 1
Vemurafenib MZ7-mel 0.0032
uM
 24
hr
 1426 16 1.0682 0.9820 0.0112 0.0137 2
Vemurafenib MZ7-mel 0.0032
uM
 24
hr
 1360 20 1.0152 0.9820 0.0147 0.0137 3
Vemurafenib MZ7-mel 0.0032
uM
 24
hr
 1363 22 1.0159 0.9820 0.0161 0.0137 4
Vemurafenib MZ7-mel 0.0032
uM
 48
hr
 3117 43 0.9517 1.0363 0.0138 0.0184 1
Vemurafenib MZ7-mel 0.0032
uM
 48
hr
 3318 46 1.0130 1.0363 0.0139 0.0184 2
Vemurafenib MZ7-mel 0.0032
uM
 48
hr
 3359 96 1.0102 1.0363 0.0286 0.0184 3
Vemurafenib MZ7-mel 0.0032
uM
 48
hr
 3847 67 1.1703 1.0363 0.0174 0.0184 4
Vemurafenib MZ7-mel 0.0032
uM
 72
hr
 3487 52 1.4309 1.2926 0.0149 0.0218 1
Vemurafenib MZ7-mel 0.0032
uM
 72
hr
 3579 56 1.4675 1.2926 0.0156 0.0218 2
Vemurafenib MZ7-mel 0.0032
uM
 72
hr
 2838 88 1.1455 1.2926 0.0310 0.0218 3