Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 MZ7-mel 0.1000
uM
 72
hr
 1446 42 0.5848 0.6143 0.0290 0.0271 4
SB590885 MZ7-mel 0.3160
uM
 24
hr
 1827 31 1.3606 1.1794 0.0170 0.0151 1
SB590885 MZ7-mel 0.3160
uM
 24
hr
 1633 22 1.2205 1.1794 0.0135 0.0151 2
SB590885 MZ7-mel 0.3160
uM
 24
hr
 1398 23 1.0417 1.1794 0.0165 0.0151 3
SB590885 MZ7-mel 0.3160
uM
 24
hr
 1465 20 1.0947 1.1794 0.0137 0.0151 4
SB590885 MZ7-mel 0.3160
uM
 48
hr
 2413 53 0.7306 0.6703 0.0220 0.0253 1
SB590885 MZ7-mel 0.3160
uM
 48
hr
 2075 53 0.6260 0.6703 0.0255 0.0253 2
SB590885 MZ7-mel 0.3160
uM
 48
hr
 2180 76 0.6514 0.6703 0.0349 0.0253 3
SB590885 MZ7-mel 0.3160
uM
 48
hr
 2216 42 0.6731 0.6703 0.0190 0.0253 4
SB590885 MZ7-mel 0.3160
uM
 72
hr
 1347 75 0.5299 0.5371 0.0557 0.0568 1
SB590885 MZ7-mel 0.3160
uM
 72
hr
 1617 76 0.6419 0.5371 0.0470 0.0568 2
SB590885 MZ7-mel 0.3160
uM
 72
hr
 1360 87 0.5303 0.5371 0.0640 0.0568 3
SB590885 MZ7-mel 0.3160
uM
 72
hr
 1141 69 0.4465 0.5371 0.0605 0.0568 4
SB590885 MZ7-mel 1.0000
uM
 24
hr
 1601 45 1.1788 1.1278 0.0281 0.0236 1
SB590885 MZ7-mel 1.0000
uM
 24
hr
 1799 26 1.3432 1.1278 0.0145 0.0236 2
SB590885 MZ7-mel 1.0000
uM
 24
hr
 1318 35 0.9720 1.1278 0.0266 0.0236 3
SB590885 MZ7-mel 1.0000
uM
 24
hr
 1378 35 1.0174 1.1278 0.0254 0.0236 4
SB590885 MZ7-mel 1.0000
uM
 48
hr
 2086 67 0.6251 0.6080 0.0321 0.0408 1
SB590885 MZ7-mel 1.0000
uM
 48
hr
 2155 78 0.6430 0.6080 0.0362 0.0408 2
SB590885 MZ7-mel 1.0000
uM
 48
hr
 1909 89 0.5635 0.6080 0.0466 0.0408 3
SB590885 MZ7-mel 1.0000
uM
 48
hr
 2038 98 0.6006 0.6080 0.0481 0.0408 4
SB590885 MZ7-mel 1.0000
uM
 72
hr
 1066 90 0.4066 0.4145 0.0844 0.0967 1
SB590885 MZ7-mel 1.0000
uM
 72
hr
 1075 90 0.4103 0.4145 0.0837 0.0967 2
SB590885 MZ7-mel 1.0000
uM
 72
hr
 1188 140 0.4365 0.4145 0.1179 0.0967 3
SB590885 MZ7-mel 1.0000
uM
 72
hr
 1080 109 0.4045 0.4145 0.1009 0.0967 4