Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | MMAC-SF | 0.1000 | uM | 48 | hr | 4273 | 174 | 1.0806 | 1.0033 | 0.0407 | 0.0439 | 1 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 48 | hr | 4127 | 189 | 1.0382 | 1.0033 | 0.0458 | 0.0439 | 2 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 48 | hr | 3653 | 165 | 0.9195 | 1.0033 | 0.0452 | 0.0439 | 3 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 48 | hr | 3868 | 170 | 0.9749 | 1.0033 | 0.0440 | 0.0439 | 4 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 72 | hr | 2566 | 90 | 0.7203 | 0.6974 | 0.0351 | 0.0382 | 1 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 72 | hr | 2430 | 102 | 0.6772 | 0.6974 | 0.0420 | 0.0382 | 2 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 72 | hr | 2560 | 85 | 0.7200 | 0.6974 | 0.0332 | 0.0382 | 3 |
| Vemurafenib | MMAC-SF | 0.1000 | uM | 72 | hr | 2413 | 103 | 0.6720 | 0.6974 | 0.0427 | 0.0382 | 4 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 24 | hr | 1 | ||||||
| Vemurafenib | MMAC-SF | 0.3160 | uM | 24 | hr | 2 | ||||||
| Vemurafenib | MMAC-SF | 0.3160 | uM | 24 | hr | 2144 | 108 | 0.7916 | 0.8897 | 0.0504 | 0.0459 | 3 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 24 | hr | 2651 | 110 | 0.9879 | 0.8897 | 0.0415 | 0.0459 | 4 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 48 | hr | 3458 | 153 | 0.8713 | 0.8499 | 0.0442 | 0.0499 | 1 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 48 | hr | 3615 | 189 | 0.9032 | 0.8499 | 0.0523 | 0.0499 | 2 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 48 | hr | 3124 | 145 | 0.7853 | 0.8499 | 0.0464 | 0.0499 | 3 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 48 | hr | 3377 | 192 | 0.8396 | 0.8499 | 0.0569 | 0.0499 | 4 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 72 | hr | 1983 | 120 | 0.5420 | 0.5601 | 0.0605 | 0.0493 | 1 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 72 | hr | 1908 | 97 | 0.5268 | 0.5601 | 0.0508 | 0.0493 | 2 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 72 | hr | 2112 | 91 | 0.5879 | 0.5601 | 0.0431 | 0.0493 | 3 |
| Vemurafenib | MMAC-SF | 0.3160 | uM | 72 | hr | 2096 | 90 | 0.5836 | 0.5601 | 0.0429 | 0.0493 | 4 |
| Vemurafenib | MMAC-SF | 1.0000 | uM | 24 | hr | 1 | ||||||
| Vemurafenib | MMAC-SF | 1.0000 | uM | 24 | hr | 2 | ||||||
| Vemurafenib | MMAC-SF | 1.0000 | uM | 24 | hr | 2491 | 119 | 0.9222 | 0.9218 | 0.0478 | 0.0484 | 3 |
| Vemurafenib | MMAC-SF | 1.0000 | uM | 24 | hr | 2492 | 122 | 0.9214 | 0.9218 | 0.0490 | 0.0484 | 4 |
| Vemurafenib | MMAC-SF | 1.0000 | uM | 48 | hr | 2676 | 167 | 0.6614 | 0.7126 | 0.0624 | 0.0573 | 1 |