Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | MMAC-SF | 0.3160 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 0.3160 | uM | 24 | hr | 2604 | 142 | 0.9572 | 0.9887 | 0.0545 | 0.0526 | 3 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 24 | hr | 2764 | 140 | 1.0202 | 0.9887 | 0.0507 | 0.0526 | 4 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 48 | hr | 3185 | 214 | 0.7832 | 0.7475 | 0.0672 | 0.0667 | 1 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 48 | hr | 3183 | 201 | 0.7861 | 0.7475 | 0.0631 | 0.0667 | 2 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 48 | hr | 2902 | 185 | 0.7163 | 0.7475 | 0.0637 | 0.0667 | 3 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 48 | hr | 2882 | 210 | 0.7044 | 0.7475 | 0.0729 | 0.0667 | 4 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 72 | hr | 1319 | 232 | 0.3162 | 0.3444 | 0.1759 | 0.1929 | 1 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 72 | hr | 1569 | 273 | 0.3770 | 0.3444 | 0.1740 | 0.1929 | 2 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 72 | hr | 1391 | 301 | 0.3171 | 0.3444 | 0.2164 | 0.1929 | 3 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 72 | hr | 1588 | 326 | 0.3671 | 0.3444 | 0.2053 | 0.1929 | 4 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 1.0000 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 1.0000 | uM | 24 | hr | 2876 | 157 | 1.0571 | 1.0390 | 0.0546 | 0.0569 | 3 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 24 | hr | 2791 | 165 | 1.0209 | 1.0390 | 0.0591 | 0.0569 | 4 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 48 | hr | 3081 | 433 | 0.6981 | 0.6637 | 0.1405 | 0.1398 | 1 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 48 | hr | 2946 | 303 | 0.6968 | 0.6637 | 0.1029 | 0.1398 | 2 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 48 | hr | 2828 | 414 | 0.6364 | 0.6637 | 0.1464 | 0.1398 | 3 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 48 | hr | 2848 | 482 | 0.6237 | 0.6637 | 0.1692 | 0.1398 | 4 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 72 | hr | 1217 | 518 | 0.2034 | 0.2100 | 0.4256 | 0.4341 | 1 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 72 | hr | 1309 | 533 | 0.2258 | 0.2100 | 0.4072 | 0.4341 | 2 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 72 | hr | 1231 | 583 | 0.1885 | 0.2100 | 0.4736 | 0.4341 | 3 |
| Selumetinib | MMAC-SF | 1.0000 | uM | 72 | hr | 1342 | 577 | 0.2226 | 0.2100 | 0.4300 | 0.4341 | 4 |
| Selumetinib | MMAC-SF | 3.1600 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 3.1600 | uM | 24 | hr | 2 |