Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 MMAC-SF 0.0316
uM
 72
hr
 2176 69 0.6130 0.6411 0.0317 0.0335 2
AZ-628 MMAC-SF 0.0316
uM
 72
hr
 2310 63 0.6537 0.6411 0.0273 0.0335 3
AZ-628 MMAC-SF 0.0316
uM
 72
hr
 2264 88 0.6330 0.6411 0.0389 0.0335 4
AZ-628 MMAC-SF 0.1000
uM
 24
hr
 1
AZ-628 MMAC-SF 0.1000
uM
 24
hr
 2
AZ-628 MMAC-SF 0.1000
uM
 24
hr
 2503 60 0.9498 0.9815 0.0240 0.0308 3
AZ-628 MMAC-SF 0.1000
uM
 24
hr
 2708 102 1.0132 0.9815 0.0377 0.0308 4
AZ-628 MMAC-SF 0.1000
uM
 48
hr
 3211 151 0.8067 0.7712 0.0470 0.0497 1
AZ-628 MMAC-SF 0.1000
uM
 48
hr
 3343 158 0.8396 0.7712 0.0473 0.0497 2
AZ-628 MMAC-SF 0.1000
uM
 48
hr
 2912 177 0.7210 0.7712 0.0608 0.0497 3
AZ-628 MMAC-SF 0.1000
uM
 48
hr
 2845 124 0.7173 0.7712 0.0436 0.0497 4
AZ-628 MMAC-SF 0.1000
uM
 72
hr
 1886 129 0.5111 0.5190 0.0684 0.0830 1
AZ-628 MMAC-SF 0.1000
uM
 72
hr
 1962 137 0.5309 0.5190 0.0698 0.0830 2
AZ-628 MMAC-SF 0.1000
uM
 72
hr
 1940 210 0.5033 0.5190 0.1083 0.0830 3
AZ-628 MMAC-SF 0.1000
uM
 72
hr
 1995 171 0.5306 0.5190 0.0857 0.0830 4
AZ-628 MMAC-SF 0.3160
uM
 24
hr
 1
AZ-628 MMAC-SF 0.3160
uM
 24
hr
 2
AZ-628 MMAC-SF 0.3160
uM
 24
hr
 2679 114 0.9972 0.9883 0.0426 0.0456 3
AZ-628 MMAC-SF 0.3160
uM
 24
hr
 2648 129 0.9794 0.9883 0.0487 0.0456 4
AZ-628 MMAC-SF 0.3160
uM
 48
hr
 3150 177 0.7838 0.7370 0.0562 0.0653 1
AZ-628 MMAC-SF 0.3160
uM
 48
hr
 3200 198 0.7914 0.7370 0.0619 0.0653 2
AZ-628 MMAC-SF 0.3160
uM
 48
hr
 2816 204 0.6886 0.7370 0.0724 0.0653 3
AZ-628 MMAC-SF 0.3160
uM
 48
hr
 2793 197 0.6844 0.7370 0.0705 0.0653 4
AZ-628 MMAC-SF 0.3160
uM
 72
hr
 1608 334 0.3706 0.3668 0.2077 0.2255 1
AZ-628 MMAC-SF 0.3160
uM
 72
hr
 1529 349 0.3433 0.3668 0.2283 0.2255 2