Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib LOXIMVI 1.0000
uM
 72
hr
 3327 1.8708 1.9365 0.0664 0.0740 2
Vemurafenib LOXIMVI 1.0000
uM
 72
hr
 3226 1.7925 1.9365 0.0775 0.0740 3
Vemurafenib LOXIMVI 1.0000
uM
 72
hr
 3094 1.7112 1.9365 0.0818 0.0740 4
Vemurafenib LOXIMVI 3.1600
uM
 24
hr
 2107 91 0.8233 0.8047 0.0432 0.0557 1
Vemurafenib LOXIMVI 3.1600
uM
 24
hr
 2348 96 0.9196 0.8047 0.0409 0.0557 2
Vemurafenib LOXIMVI 3.1600
uM
 24
hr
 1770 121 0.6734 0.8047 0.0684 0.0557 3
Vemurafenib LOXIMVI 3.1600
uM
 24
hr
 2114 149 0.8024 0.8047 0.0705 0.0557 4
Vemurafenib LOXIMVI 3.1600
uM
 48
hr
 1757 1.0871 1.0470 0.0797 0.0897 1
Vemurafenib LOXIMVI 3.1600
uM
 48
hr
 1590 0.9775 1.0470 0.0855 0.0897 2
Vemurafenib LOXIMVI 3.1600
uM
 48
hr
 1769 1.0784 1.0470 0.0933 0.0897 3
Vemurafenib LOXIMVI 3.1600
uM
 48
hr
 1727 1.0448 1.0470 0.1002 0.0897 4
Vemurafenib LOXIMVI 3.1600
uM
 72
hr
 2196 1.1619 1.0205 0.1216 0.1290 1
Vemurafenib LOXIMVI 3.1600
uM
 72
hr
 1872 0.9902 1.0205 0.1218 0.1290 2
Vemurafenib LOXIMVI 3.1600
uM
 72
hr
 1988 1.0342 1.0205 0.1363 0.1290 3
Vemurafenib LOXIMVI 3.1600
uM
 72
hr
 1722 0.8957 1.0205 0.1365 0.1290 4
LOXIMVI 0.0000
uM
 24
hr
 2557 119 0.9956 0.0465 1
LOXIMVI 0.0000
uM
 24
hr
 2797 208 1.0572 0.0744 1
LOXIMVI 0.0000
uM
 24
hr
 2946 106 1.1597 0.0360 1
LOXIMVI 0.0000
uM
 24
hr
 3043 205 1.1589 0.0674 1
LOXIMVI 0.0000
uM
 24
hr
 3056 143 1.1896 0.0468 1
LOXIMVI 0.0000
uM
 24
hr
 3080 170 1.1883 0.0552 1
LOXIMVI 0.0000
uM
 24
hr
 3113 159 1.2063 0.0511 1
LOXIMVI 0.0000
uM
 24
hr
 2503 131 0.9686 0.0523 2
LOXIMVI 0.0000
uM
 24
hr
 2505 144 0.9641 0.0575 2
LOXIMVI 0.0000
uM
 24
hr
 2670 176 1.0185 0.0659 2