Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM1552C | 0.3160 | uM | 24 | hr | 2751 | 212 | 1.0134 | 1.0315 | 0.0771 | 0.0682 | 1 |
| Vemurafenib | WM1552C | 0.3160 | uM | 24 | hr | 2796 | 166 | 1.0497 | 1.0315 | 0.0594 | 0.0682 | 2 |
| Vemurafenib | WM1552C | 0.3160 | uM | 24 | hr | 3 | ||||||
| Vemurafenib | WM1552C | 0.3160 | uM | 24 | hr | 4 | ||||||
| Vemurafenib | WM1552C | 0.3160 | uM | 48 | hr | 3378 | 181 | 1.0170 | 1.0577 | 0.0536 | 0.0630 | 1 |
| Vemurafenib | WM1552C | 0.3160 | uM | 48 | hr | 3382 | 203 | 1.0112 | 1.0577 | 0.0600 | 0.0630 | 2 |
| Vemurafenib | WM1552C | 0.3160 | uM | 48 | hr | 3892 | 293 | 1.1448 | 1.0577 | 0.0753 | 0.0630 | 3 |
| Vemurafenib | WM1552C | 0.3160 | uM | 48 | hr | 4 | ||||||
| Vemurafenib | WM1552C | 0.3160 | uM | 72 | hr | 6472 | 434 | 1.1711 | 1.0551 | 0.0671 | 0.0671 | 1 |
| Vemurafenib | WM1552C | 0.3160 | uM | 72 | hr | 6066 | 368 | 1.1052 | 1.0551 | 0.0607 | 0.0671 | 2 |
| Vemurafenib | WM1552C | 0.3160 | uM | 72 | hr | 5504 | 395 | 0.9910 | 1.0551 | 0.0718 | 0.0671 | 3 |
| Vemurafenib | WM1552C | 0.3160 | uM | 72 | hr | 5278 | 364 | 0.9531 | 1.0551 | 0.0690 | 0.0671 | 4 |
| Vemurafenib | WM1552C | 1.0000 | uM | 24 | hr | 2650 | 218 | 0.9707 | 0.9874 | 0.0823 | 0.0745 | 1 |
| Vemurafenib | WM1552C | 1.0000 | uM | 24 | hr | 2696 | 180 | 1.0042 | 0.9874 | 0.0668 | 0.0745 | 2 |
| Vemurafenib | WM1552C | 1.0000 | uM | 24 | hr | 3 | ||||||
| Vemurafenib | WM1552C | 1.0000 | uM | 24 | hr | 4 | ||||||
| Vemurafenib | WM1552C | 1.0000 | uM | 48 | hr | 2990 | 158 | 0.9009 | 0.8856 | 0.0528 | 0.0641 | 1 |
| Vemurafenib | WM1552C | 1.0000 | uM | 48 | hr | 2932 | 135 | 0.8897 | 0.8856 | 0.0460 | 0.0641 | 2 |
| Vemurafenib | WM1552C | 1.0000 | uM | 48 | hr | 2994 | 237 | 0.8770 | 0.8856 | 0.0792 | 0.0641 | 3 |
| Vemurafenib | WM1552C | 1.0000 | uM | 48 | hr | 2984 | 234 | 0.8748 | 0.8856 | 0.0784 | 0.0641 | 4 |
| Vemurafenib | WM1552C | 1.0000 | uM | 72 | hr | 3927 | 342 | 0.6954 | 0.6712 | 0.0871 | 0.0874 | 1 |
| Vemurafenib | WM1552C | 1.0000 | uM | 72 | hr | 4155 | 338 | 0.7404 | 0.6712 | 0.0813 | 0.0874 | 2 |
| Vemurafenib | WM1552C | 1.0000 | uM | 72 | hr | 3476 | 312 | 0.6137 | 0.6712 | 0.0898 | 0.0874 | 3 |
| Vemurafenib | WM1552C | 1.0000 | uM | 72 | hr | 3605 | 329 | 0.6354 | 0.6712 | 0.0913 | 0.0874 | 4 |
| Vemurafenib | WM1552C | 3.1600 | uM | 24 | hr | 2246 | 147 | 0.8378 | 0.8753 | 0.0655 | 0.0696 | 1 |