Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM1552C | 0.0100 | uM | 72 | hr | 6547 | 560 | 1.1613 | 1.1384 | 0.0855 | 0.0756 | 4 |
| Vemurafenib | WM1552C | 0.0316 | uM | 24 | hr | 2345 | 138 | 0.8809 | 0.9124 | 0.0588 | 0.0602 | 1 |
| Vemurafenib | WM1552C | 0.0316 | uM | 24 | hr | 2520 | 155 | 0.9439 | 0.9124 | 0.0615 | 0.0602 | 2 |
| Vemurafenib | WM1552C | 0.0316 | uM | 24 | hr | 3 | ||||||
| Vemurafenib | WM1552C | 0.0316 | uM | 24 | hr | 4 | ||||||
| Vemurafenib | WM1552C | 0.0316 | uM | 48 | hr | 3503 | 238 | 1.0386 | 1.0084 | 0.0679 | 0.0688 | 1 |
| Vemurafenib | WM1552C | 0.0316 | uM | 48 | hr | 3288 | 183 | 0.9877 | 1.0084 | 0.0557 | 0.0688 | 2 |
| Vemurafenib | WM1552C | 0.0316 | uM | 48 | hr | 3173 | 239 | 0.9333 | 1.0084 | 0.0753 | 0.0688 | 3 |
| Vemurafenib | WM1552C | 0.0316 | uM | 48 | hr | 3655 | 279 | 1.0739 | 1.0084 | 0.0763 | 0.0688 | 4 |
| Vemurafenib | WM1552C | 0.0316 | uM | 72 | hr | 7052 | 542 | 1.2627 | 1.1735 | 0.0769 | 0.0733 | 1 |
| Vemurafenib | WM1552C | 0.0316 | uM | 72 | hr | 7084 | 433 | 1.2900 | 1.1735 | 0.0611 | 0.0733 | 2 |
| Vemurafenib | WM1552C | 0.0316 | uM | 72 | hr | 6209 | 494 | 1.1085 | 1.1735 | 0.0796 | 0.0733 | 3 |
| Vemurafenib | WM1552C | 0.0316 | uM | 72 | hr | 5761 | 436 | 1.0329 | 1.1735 | 0.0757 | 0.0733 | 4 |
| Vemurafenib | WM1552C | 0.1000 | uM | 24 | hr | 2698 | 168 | 1.0098 | 1.0575 | 0.0623 | 0.0665 | 1 |
| Vemurafenib | WM1552C | 0.1000 | uM | 24 | hr | 2980 | 211 | 1.1052 | 1.0575 | 0.0708 | 0.0665 | 2 |
| Vemurafenib | WM1552C | 0.1000 | uM | 24 | hr | 3 | ||||||
| Vemurafenib | WM1552C | 0.1000 | uM | 24 | hr | 4 | ||||||
| Vemurafenib | WM1552C | 0.1000 | uM | 48 | hr | 3350 | 211 | 0.9985 | 1.0001 | 0.0630 | 0.0684 | 1 |
| Vemurafenib | WM1552C | 0.1000 | uM | 48 | hr | 3491 | 193 | 1.0491 | 1.0001 | 0.0553 | 0.0684 | 2 |
| Vemurafenib | WM1552C | 0.1000 | uM | 48 | hr | 3451 | 273 | 1.0109 | 1.0001 | 0.0791 | 0.0684 | 3 |
| Vemurafenib | WM1552C | 0.1000 | uM | 48 | hr | 3206 | 245 | 0.9419 | 1.0001 | 0.0764 | 0.0684 | 4 |
| Vemurafenib | WM1552C | 0.1000 | uM | 72 | hr | 7462 | 516 | 1.3473 | 1.2023 | 0.0692 | 0.0668 | 1 |
| Vemurafenib | WM1552C | 0.1000 | uM | 72 | hr | 7014 | 424 | 1.2782 | 1.2023 | 0.0605 | 0.0668 | 2 |
| Vemurafenib | WM1552C | 0.1000 | uM | 72 | hr | 6022 | 406 | 1.0893 | 1.2023 | 0.0674 | 0.0668 | 3 |
| Vemurafenib | WM1552C | 0.1000 | uM | 72 | hr | 6068 | 425 | 1.0945 | 1.2023 | 0.0700 | 0.0668 | 4 |