Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | WM1552C | 1.0000 | uM | 48 | hr | 2128 | 238 | 0.6012 | 0.6475 | 0.1118 | 0.0857 | 3 |
| AZ-628 | WM1552C | 1.0000 | uM | 48 | hr | 2186 | 199 | 0.6321 | 0.6475 | 0.0910 | 0.0857 | 4 |
| AZ-628 | WM1552C | 1.0000 | uM | 72 | hr | 3134 | 486 | 0.5136 | 0.4844 | 0.1551 | 0.1535 | 1 |
| AZ-628 | WM1552C | 1.0000 | uM | 72 | hr | 3198 | 494 | 0.5245 | 0.4844 | 0.1545 | 0.1535 | 2 |
| AZ-628 | WM1552C | 1.0000 | uM | 72 | hr | 2694 | 427 | 0.4397 | 0.4844 | 0.1585 | 0.1535 | 3 |
| AZ-628 | WM1552C | 1.0000 | uM | 72 | hr | 2776 | 405 | 0.4599 | 0.4844 | 0.1459 | 0.1535 | 4 |
| AZ-628 | WM1552C | 3.1600 | uM | 24 | hr | 2543 | 297 | 0.8964 | 0.9282 | 0.1168 | 0.1043 | 1 |
| AZ-628 | WM1552C | 3.1600 | uM | 24 | hr | 2648 | 243 | 0.9599 | 0.9282 | 0.0918 | 0.1043 | 2 |
| AZ-628 | WM1552C | 3.1600 | uM | 24 | hr | 3 | ||||||
| AZ-628 | WM1552C | 3.1600 | uM | 24 | hr | 4 | ||||||
| AZ-628 | WM1552C | 3.1600 | uM | 48 | hr | 2361 | 199 | 0.6877 | 0.6444 | 0.0843 | 0.1080 | 1 |
| AZ-628 | WM1552C | 3.1600 | uM | 48 | hr | 2226 | 177 | 0.6518 | 0.6444 | 0.0795 | 0.1080 | 2 |
| AZ-628 | WM1552C | 3.1600 | uM | 48 | hr | 2198 | 271 | 0.6130 | 0.6444 | 0.1233 | 0.1080 | 3 |
| AZ-628 | WM1552C | 3.1600 | uM | 48 | hr | 2298 | 333 | 0.6251 | 0.6444 | 0.1449 | 0.1080 | 4 |
| AZ-628 | WM1552C | 3.1600 | uM | 72 | hr | 2859 | 490 | 0.4595 | 0.4415 | 0.1714 | 0.1723 | 1 |
| AZ-628 | WM1552C | 3.1600 | uM | 72 | hr | 2985 | 494 | 0.4832 | 0.4415 | 0.1655 | 0.1723 | 2 |
| AZ-628 | WM1552C | 3.1600 | uM | 72 | hr | 2632 | 478 | 0.4178 | 0.4415 | 0.1816 | 0.1723 | 3 |
| AZ-628 | WM1552C | 3.1600 | uM | 72 | hr | 2521 | 430 | 0.4056 | 0.4415 | 0.1706 | 0.1723 | 4 |
| Selumetinib | WM1552C | 0.0032 | uM | 24 | hr | 2536 | 127 | 0.9615 | 0.9701 | 0.0501 | 0.0571 | 1 |
| Selumetinib | WM1552C | 0.0032 | uM | 24 | hr | 2620 | 168 | 0.9786 | 0.9701 | 0.0641 | 0.0571 | 2 |
| Selumetinib | WM1552C | 0.0032 | uM | 24 | hr | 3 | ||||||
| Selumetinib | WM1552C | 0.0032 | uM | 24 | hr | 4 | ||||||
| Selumetinib | WM1552C | 0.0032 | uM | 48 | hr | 3154 | 195 | 0.9413 | 0.9467 | 0.0618 | 0.0650 | 1 |
| Selumetinib | WM1552C | 0.0032 | uM | 48 | hr | 3122 | 168 | 0.9397 | 0.9467 | 0.0538 | 0.0650 | 2 |
| Selumetinib | WM1552C | 0.0032 | uM | 48 | hr | 3409 | 258 | 1.0023 | 0.9467 | 0.0757 | 0.0650 | 3 |