Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib SKMEL28 0.1000
uM
 24
hr
 2
Selumetinib SKMEL28 0.1000
uM
 24
hr
 3
Selumetinib SKMEL28 0.1000
uM
 24
hr
 4
Selumetinib SKMEL28 0.1000
uM
 48
hr
 2156 83 1.2347 1.1168 0.0385 0.0355 1
Selumetinib SKMEL28 0.1000
uM
 48
hr
 2023 62 1.1680 1.1168 0.0306 0.0355 2
Selumetinib SKMEL28 0.1000
uM
 48
hr
 1824 61 1.0500 1.1168 0.0334 0.0355 3
Selumetinib SKMEL28 0.1000
uM
 48
hr
 1773 70 1.0143 1.1168 0.0395 0.0355 4
Selumetinib SKMEL28 0.1000
uM
 72
hr
 727 23 0.5281 0.5435 0.0316 0.0370 1
Selumetinib SKMEL28 0.1000
uM
 72
hr
 775 32 0.5573 0.5435 0.0413 0.0370 2
Selumetinib SKMEL28 0.1000
uM
 72
hr
 689 23 0.4996 0.5435 0.0334 0.0370 3
Selumetinib SKMEL28 0.1000
uM
 72
hr
 819 34 0.5888 0.5435 0.0415 0.0370 4
Selumetinib SKMEL28 0.3160
uM
 24
hr
 1
Selumetinib SKMEL28 0.3160
uM
 24
hr
 2
Selumetinib SKMEL28 0.3160
uM
 24
hr
 3
Selumetinib SKMEL28 0.3160
uM
 24
hr
 4
Selumetinib SKMEL28 0.3160
uM
 48
hr
 1717 60 0.9869 0.9635 0.0349 0.0422 1
Selumetinib SKMEL28 0.3160
uM
 48
hr
 1853 84 1.0536 0.9635 0.0453 0.0422 2
Selumetinib SKMEL28 0.3160
uM
 48
hr
 1602 79 0.9071 0.9635 0.0493 0.0422 3
Selumetinib SKMEL28 0.3160
uM
 48
hr
 1584 62 0.9065 0.9635 0.0391 0.0422 4
Selumetinib SKMEL28 0.3160
uM
 72
hr
 575 45 0.3976 0.4490 0.0783 0.0563 1
Selumetinib SKMEL28 0.3160
uM
 72
hr
 652 24 0.4711 0.4490 0.0368 0.0563 2
Selumetinib SKMEL28 0.3160
uM
 72
hr
 568 38 0.3976 0.4490 0.0669 0.0563 3
Selumetinib SKMEL28 0.3160
uM
 72
hr
 738 32 0.5296 0.4490 0.0434 0.0563 4
Selumetinib SKMEL28 1.0000
uM
 24
hr
 1
Selumetinib SKMEL28 1.0000
uM
 24
hr
 2