Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib K2 1.0000
uM
 48
hr
 1172 250 0.3365 0.5049 0.2133 0.1987 3
Selumetinib K2 1.0000
uM
 48
hr
 1145 251 0.3263 0.5049 0.2192 0.1987 4
Selumetinib K2 1.0000
uM
 72
hr
 1
Selumetinib K2 1.0000
uM
 72
hr
 2
Selumetinib K2 1.0000
uM
 72
hr
 3
Selumetinib K2 1.0000
uM
 72
hr
 4
Selumetinib K2 3.1600
uM
 24
hr
 1208 140 0.6281 0.5493 0.1159 0.1419 1
Selumetinib K2 3.1600
uM
 24
hr
 1393 165 0.7222 0.5493 0.1185 0.1419 2
Selumetinib K2 3.1600
uM
 24
hr
 752 137 0.3617 0.5493 0.1822 0.1419 3
Selumetinib K2 3.1600
uM
 24
hr
 972 147 0.4852 0.5493 0.1512 0.1419 4
Selumetinib K2 3.1600
uM
 48
hr
 2663 852 0.6609 0.5313 0.3199 0.3324 1
Selumetinib K2 3.1600
uM
 48
hr
 2766 873 0.6908 0.5313 0.3156 0.3324 2
Selumetinib K2 3.1600
uM
 48
hr
 1495 505 0.3613 0.5313 0.3378 0.3324 3
Selumetinib K2 3.1600
uM
 48
hr
 1754 625 0.4120 0.5313 0.3563 0.3324 4
Selumetinib K2 3.1600
uM
 72
hr
 1
Selumetinib K2 3.1600
uM
 72
hr
 2
Selumetinib K2 3.1600
uM
 72
hr
 3
Selumetinib K2 3.1600
uM
 72
hr
 4
Vemurafenib K2 0.0032
uM
 24
hr
 3039 14 1.7791 1.7736 0.0046 0.0042 1
Vemurafenib K2 0.0032
uM
 24
hr
 3262 11 1.9120 1.7736 0.0034 0.0042 2
Vemurafenib K2 0.0032
uM
 24
hr
 2746 13 1.6074 1.7736 0.0047 0.0042 3
Vemurafenib K2 0.0032
uM
 24
hr
 3066 12 1.7961 1.7736 0.0039 0.0042 4
Vemurafenib K2 0.0032
uM
 48
hr
 3821 6 1.3923 1.4412 0.0016 0.0031 1
Vemurafenib K2 0.0032
uM
 48
hr
 3938 13 1.4324 1.4412 0.0033 0.0031 2
Vemurafenib K2 0.0032
uM
 48
hr
 4162 20 1.5116 1.4412 0.0048 0.0031 3