Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib K2 0.1000
uM
 48
hr
 2322 95 0.8127 0.5919 0.0409 0.0372 2
Selumetinib K2 0.1000
uM
 48
hr
 1237 41 0.4365 0.5919 0.0331 0.0372 3
Selumetinib K2 0.1000
uM
 48
hr
 1503 42 0.5332 0.5919 0.0279 0.0372 4
Selumetinib K2 0.1000
uM
 72
hr
 1
Selumetinib K2 0.1000
uM
 72
hr
 2
Selumetinib K2 0.1000
uM
 72
hr
 3
Selumetinib K2 0.1000
uM
 72
hr
 4
Selumetinib K2 0.3160
uM
 24
hr
 985 29 0.5623 0.4918 0.0294 0.0266 1
Selumetinib K2 0.3160
uM
 24
hr
 1150 10 0.6705 0.4918 0.0087 0.0266 2
Selumetinib K2 0.3160
uM
 24
hr
 619 22 0.3511 0.4918 0.0355 0.0266 3
Selumetinib K2 0.3160
uM
 24
hr
 674 22 0.3835 0.4918 0.0326 0.0266 4
Selumetinib K2 0.3160
uM
 48
hr
 1914 131 0.6507 0.5403 0.0684 0.0691 1
Selumetinib K2 0.3160
uM
 48
hr
 2386 124 0.8255 0.5403 0.0520 0.0691 2
Selumetinib K2 0.3160
uM
 48
hr
 977 83 0.3263 0.5403 0.0850 0.0691 3
Selumetinib K2 0.3160
uM
 48
hr
 1058 75 0.3587 0.5403 0.0709 0.0691 4
Selumetinib K2 0.3160
uM
 72
hr
 1
Selumetinib K2 0.3160
uM
 72
hr
 2
Selumetinib K2 0.3160
uM
 72
hr
 3
Selumetinib K2 0.3160
uM
 72
hr
 4
Selumetinib K2 1.0000
uM
 24
hr
 1268 131 0.6687 0.6109 0.1033 0.1228 1
Selumetinib K2 1.0000
uM
 24
hr
 1631 125 0.8857 0.6109 0.0766 0.1228 2
Selumetinib K2 1.0000
uM
 24
hr
 746 122 0.3670 0.6109 0.1635 0.1228 3
Selumetinib K2 1.0000
uM
 24
hr
 1042 154 0.5223 0.6109 0.1478 0.1228 4
Selumetinib K2 1.0000
uM
 48
hr
 2116 402 0.6255 0.5049 0.1900 0.1987 1
Selumetinib K2 1.0000
uM
 48
hr
 2421 417 0.7314 0.5049 0.1722 0.1987 2