Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib K2 0.0100
uM
 48
hr
 2248 6 0.8182 0.9590 0.0027 0.0033 1
Selumetinib K2 0.0100
uM
 48
hr
 2925 6 1.0653 0.9590 0.0021 0.0033 2
Selumetinib K2 0.0100
uM
 48
hr
 2524 10 0.9175 0.9590 0.0040 0.0033 3
Selumetinib K2 0.0100
uM
 48
hr
 2849 13 1.0350 0.9590 0.0046 0.0033 4
Selumetinib K2 0.0100
uM
 72
hr
 1
Selumetinib K2 0.0100
uM
 72
hr
 2
Selumetinib K2 0.0100
uM
 72
hr
 3
Selumetinib K2 0.0100
uM
 72
hr
 4
Selumetinib K2 0.0316
uM
 24
hr
 1941 3 1.1398 1.0203 0.0015 0.0045 1
Selumetinib K2 0.0316
uM
 24
hr
 2368 5 1.3897 1.0203 0.0021 0.0045 2
Selumetinib K2 0.0316
uM
 24
hr
 1248 11 0.7275 1.0203 0.0088 0.0045 3
Selumetinib K2 0.0316
uM
 24
hr
 1409 8 0.8240 1.0203 0.0057 0.0045 4
Selumetinib K2 0.0316
uM
 48
hr
 2003 9 0.7277 0.8224 0.0045 0.0058 1
Selumetinib K2 0.0316
uM
 48
hr
 2357 13 0.8554 0.8224 0.0055 0.0058 2
Selumetinib K2 0.0316
uM
 48
hr
 2273 16 0.8237 0.8224 0.0070 0.0058 3
Selumetinib K2 0.0316
uM
 48
hr
 2434 15 0.8828 0.8224 0.0062 0.0058 4
Selumetinib K2 0.0316
uM
 72
hr
 1
Selumetinib K2 0.0316
uM
 72
hr
 2
Selumetinib K2 0.0316
uM
 72
hr
 3
Selumetinib K2 0.0316
uM
 72
hr
 4
Selumetinib K2 0.1000
uM
 24
hr
 1055 13 0.6128 0.6297 0.0123 0.0128 1
Selumetinib K2 0.1000
uM
 24
hr
 1611 13 0.9398 0.6297 0.0081 0.0128 2
Selumetinib K2 0.1000
uM
 24
hr
 750 14 0.4329 0.6297 0.0187 0.0128 3
Selumetinib K2 0.1000
uM
 24
hr
 918 11 0.5334 0.6297 0.0120 0.0128 4
Selumetinib K2 0.1000
uM
 48
hr
 1683 79 0.5854 0.5919 0.0469 0.0372 1