Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 K2 3.1600
uM
 24
hr
 842 151 0.4064 0.7194 0.1793 0.1355 4
AZ-628 K2 3.1600
uM
 48
hr
 2875 862 0.7346 0.5330 0.2998 0.3577 1
AZ-628 K2 3.1600
uM
 48
hr
 3215 1154 0.7522 0.5330 0.3589 0.3577 2
AZ-628 K2 3.1600
uM
 48
hr
 1430 512 0.3350 0.5330 0.3580 0.3577 3
AZ-628 K2 3.1600
uM
 48
hr
 1450 600 0.3102 0.5330 0.4138 0.3577 4
AZ-628 K2 3.1600
uM
 72
hr
 1
AZ-628 K2 3.1600
uM
 72
hr
 2
AZ-628 K2 3.1600
uM
 72
hr
 3
AZ-628 K2 3.1600
uM
 72
hr
 4
Selumetinib K2 0.0032
uM
 24
hr
 2163 13 1.2645 1.1566 0.0060 0.0051 1
Selumetinib K2 0.0032
uM
 24
hr
 1915 7 1.1221 1.1566 0.0037 0.0051 2
Selumetinib K2 0.0032
uM
 24
hr
 1711 10 1.0004 1.1566 0.0058 0.0051 3
Selumetinib K2 0.0032
uM
 24
hr
 2117 10 1.2392 1.1566 0.0047 0.0051 4
Selumetinib K2 0.0032
uM
 48
hr
 3572 7 1.3010 1.1652 0.0020 0.0027 1
Selumetinib K2 0.0032
uM
 48
hr
 3377 5 1.2306 1.1652 0.0015 0.0027 2
Selumetinib K2 0.0032
uM
 48
hr
 2629 12 0.9551 1.1652 0.0046 0.0027 3
Selumetinib K2 0.0032
uM
 48
hr
 3226 9 1.1740 1.1652 0.0028 0.0027 4
Selumetinib K2 0.0032
uM
 72
hr
 1
Selumetinib K2 0.0032
uM
 72
hr
 2
Selumetinib K2 0.0032
uM
 72
hr
 3
Selumetinib K2 0.0032
uM
 72
hr
 4
Selumetinib K2 0.0100
uM
 24
hr
 2285 6 1.3403 1.1449 0.0026 0.0032 1
Selumetinib K2 0.0100
uM
 24
hr
 2384 11 1.3956 1.1449 0.0046 0.0032 2
Selumetinib K2 0.0100
uM
 24
hr
 1521 1 0.8940 1.1449 0.0007 0.0032 3
Selumetinib K2 0.0100
uM
 24
hr
 1623 8 0.9498 1.1449 0.0049 0.0032 4