Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | MZ7-mel | 0.0032 | uM | 72 | hr | 2775 | 71 | 1.1264 | 1.2926 | 0.0256 | 0.0218 | 4 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 24 | hr | 1775 | 34 | 1.3189 | 1.1080 | 0.0192 | 0.0131 | 1 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 24 | hr | 1748 | 21 | 1.3083 | 1.1080 | 0.0120 | 0.0131 | 2 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 24 | hr | 1159 | 7 | 0.8727 | 1.1080 | 0.0060 | 0.0131 | 3 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 24 | hr | 1249 | 19 | 0.9318 | 1.1080 | 0.0152 | 0.0131 | 4 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 48 | hr | 3434 | 38 | 1.0514 | 1.0916 | 0.0111 | 0.0167 | 1 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 48 | hr | 3249 | 35 | 0.9950 | 1.0916 | 0.0108 | 0.0167 | 2 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 48 | hr | 3851 | 93 | 1.1635 | 1.0916 | 0.0242 | 0.0167 | 3 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 48 | hr | 3814 | 79 | 1.1563 | 1.0916 | 0.0207 | 0.0167 | 4 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 72 | hr | 3622 | 53 | 1.4867 | 1.3886 | 0.0146 | 0.0158 | 1 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 72 | hr | 3408 | 54 | 1.3971 | 1.3886 | 0.0158 | 0.0158 | 2 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 72 | hr | 3131 | 53 | 1.2822 | 1.3886 | 0.0169 | 0.0158 | 3 |
| Vemurafenib | MZ7-mel | 0.0100 | uM | 72 | hr | 4 | ||||||
| Vemurafenib | MZ7-mel | 0.0316 | uM | 24 | hr | 1483 | 5 | 1.1197 | 1.0795 | 0.0034 | 0.0072 | 1 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 24 | hr | 1669 | 9 | 1.2576 | 1.0795 | 0.0054 | 0.0072 | 2 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 24 | hr | 1267 | 13 | 0.9500 | 1.0795 | 0.0103 | 0.0072 | 3 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 24 | hr | 1321 | 13 | 0.9909 | 1.0795 | 0.0098 | 0.0072 | 4 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 48 | hr | 3662 | 51 | 1.1179 | 1.0675 | 0.0139 | 0.0196 | 1 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 48 | hr | 3654 | 47 | 1.1167 | 1.0675 | 0.0129 | 0.0196 | 2 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 48 | hr | 3276 | 104 | 0.9820 | 1.0675 | 0.0317 | 0.0196 | 3 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 48 | hr | 3471 | 69 | 1.0532 | 1.0675 | 0.0199 | 0.0196 | 4 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 72 | hr | 3232 | 29 | 1.3342 | 1.1850 | 0.0090 | 0.0159 | 1 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 72 | hr | 3488 | 43 | 1.4350 | 1.1850 | 0.0123 | 0.0159 | 2 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 72 | hr | 2956 | 39 | 1.2151 | 1.1850 | 0.0132 | 0.0159 | 3 |
| Vemurafenib | MZ7-mel | 0.0316 | uM | 72 | hr | 1868 | 54 | 0.7556 | 1.1850 | 0.0289 | 0.0159 | 4 |