Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib MZ7-mel 0.1000
uM
 72
hr
 760 71 0.2870 0.3280 0.0934 0.1076 2
Selumetinib MZ7-mel 0.1000
uM
 72
hr
 852 116 0.3066 0.3280 0.1362 0.1076 3
Selumetinib MZ7-mel 0.1000
uM
 72
hr
 1106 120 0.4107 0.3280 0.1085 0.1076 4
Selumetinib MZ7-mel 0.3160
uM
 24
hr
 1530 33 1.1341 1.0672 0.0216 0.0210 1
Selumetinib MZ7-mel 0.3160
uM
 24
hr
 1658 34 1.2303 1.0672 0.0205 0.0210 2
Selumetinib MZ7-mel 0.3160
uM
 24
hr
 1271 22 0.9462 1.0672 0.0173 0.0210 3
Selumetinib MZ7-mel 0.3160
uM
 24
hr
 1297 32 0.9583 1.0672 0.0247 0.0210 4
Selumetinib MZ7-mel 0.3160
uM
 48
hr
 1569 47 0.4712 0.5082 0.0300 0.0385 1
Selumetinib MZ7-mel 0.3160
uM
 48
hr
 1689 82 0.4975 0.5082 0.0485 0.0385 2
Selumetinib MZ7-mel 0.3160
uM
 48
hr
 1799 64 0.5372 0.5082 0.0356 0.0385 3
Selumetinib MZ7-mel 0.3160
uM
 48
hr
 1773 71 0.5269 0.5082 0.0400 0.0385 4
Selumetinib MZ7-mel 0.3160
uM
 72
hr
 987 124 0.3595 0.3495 0.1256 0.1580 1
Selumetinib MZ7-mel 0.3160
uM
 72
hr
 997 120 0.3653 0.3495 0.1204 0.1580 2
Selumetinib MZ7-mel 0.3160
uM
 72
hr
 1011 181 0.3457 0.3495 0.1790 0.1580 3
Selumetinib MZ7-mel 0.3160
uM
 72
hr
 991 205 0.3274 0.3495 0.2069 0.1580 4
Selumetinib MZ7-mel 1.0000
uM
 24
hr
 1537 39 1.1348 0.9970 0.0254 0.0300 1
Selumetinib MZ7-mel 1.0000
uM
 24
hr
 1570 56 1.1470 0.9970 0.0357 0.0300 2
Selumetinib MZ7-mel 1.0000
uM
 24
hr
 1209 29 0.8939 0.9970 0.0240 0.0300 3
Selumetinib MZ7-mel 1.0000
uM
 24
hr
 1111 39 0.8121 0.9970 0.0351 0.0300 4
Selumetinib MZ7-mel 1.0000
uM
 48
hr
 1756 95 0.5142 0.5044 0.0541 0.0514 1
Selumetinib MZ7-mel 1.0000
uM
 48
hr
 1788 88 0.5263 0.5044 0.0492 0.0514 2
Selumetinib MZ7-mel 1.0000
uM
 48
hr
 1823 92 0.5359 0.5044 0.0505 0.0514 3
Selumetinib MZ7-mel 1.0000
uM
 48
hr
 1503 78 0.4412 0.5044 0.0519 0.0514 4
Selumetinib MZ7-mel 1.0000
uM
 72
hr
 725 153 0.2383 0.3076 0.2110 0.2389 1
Selumetinib MZ7-mel 1.0000
uM
 72
hr
 957 180 0.3237 0.3076 0.1881 0.2389 2