Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib MZ7-mel 0.0100
uM
 72
hr
 2735 43 1.1214 1.0587 0.0157 0.0173 1
Selumetinib MZ7-mel 0.0100
uM
 72
hr
 2966 42 1.2180 1.0587 0.0142 0.0173 2
Selumetinib MZ7-mel 0.0100
uM
 72
hr
 2177 49 0.8864 1.0587 0.0225 0.0173 3
Selumetinib MZ7-mel 0.0100
uM
 72
hr
 2463 41 1.0089 1.0587 0.0166 0.0173 4
Selumetinib MZ7-mel 0.0316
uM
 24
hr
 1686 32 1.2530 1.1074 0.0190 0.0129 1
Selumetinib MZ7-mel 0.0316
uM
 24
hr
 1613 17 1.2091 1.1074 0.0105 0.0129 2
Selumetinib MZ7-mel 0.0316
uM
 24
hr
 1369 16 1.0250 1.1074 0.0117 0.0129 3
Selumetinib MZ7-mel 0.0316
uM
 24
hr
 1257 13 0.9424 1.1074 0.0103 0.0129 4
Selumetinib MZ7-mel 0.0316
uM
 48
hr
 3464 24 1.0650 1.0395 0.0069 0.0142 1
Selumetinib MZ7-mel 0.0316
uM
 48
hr
 2986 27 0.9161 1.0395 0.0090 0.0142 2
Selumetinib MZ7-mel 0.0316
uM
 48
hr
 3554 79 1.0758 1.0395 0.0222 0.0142 3
Selumetinib MZ7-mel 0.0316
uM
 48
hr
 3623 67 1.1009 1.0395 0.0185 0.0142 4
Selumetinib MZ7-mel 0.0316
uM
 72
hr
 1675 49 0.6773 0.5802 0.0293 0.0366 1
Selumetinib MZ7-mel 0.0316
uM
 72
hr
 1325 32 0.5386 0.5802 0.0242 0.0366 2
Selumetinib MZ7-mel 0.0316
uM
 72
hr
 1371 73 0.5407 0.5802 0.0532 0.0366 3
Selumetinib MZ7-mel 0.0316
uM
 72
hr
 1410 56 0.5640 0.5802 0.0397 0.0366 4
Selumetinib MZ7-mel 0.1000
uM
 24
hr
 1500 18 1.1227 1.0706 0.0120 0.0130 1
Selumetinib MZ7-mel 0.1000
uM
 24
hr
 1477 15 1.1076 1.0706 0.0102 0.0130 2
Selumetinib MZ7-mel 0.1000
uM
 24
hr
 1341 18 1.0023 1.0706 0.0134 0.0130 3
Selumetinib MZ7-mel 0.1000
uM
 24
hr
 1409 23 1.0500 1.0706 0.0163 0.0130 4
Selumetinib MZ7-mel 0.1000
uM
 48
hr
 2607 53 0.7907 0.7966 0.0203 0.0195 1
Selumetinib MZ7-mel 0.1000
uM
 48
hr
 2541 40 0.7743 0.7966 0.0157 0.0195 2
Selumetinib MZ7-mel 0.1000
uM
 48
hr
 2682 56 0.8130 0.7966 0.0209 0.0195 3
Selumetinib MZ7-mel 0.1000
uM
 48
hr
 2667 56 0.8084 0.7966 0.0210 0.0195 4
Selumetinib MZ7-mel 0.1000
uM
 72
hr
 814 75 0.3078 0.3280 0.0921 0.1076 1