Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | MZ7-mel | 0.0032 | uM | 48 | hr | 2788 | 34 | 0.8526 | 1.0337 | 0.0122 | 0.0137 | 1 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 48 | hr | 3199 | 62 | 0.9712 | 1.0337 | 0.0194 | 0.0137 | 2 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 48 | hr | 3561 | 39 | 1.0904 | 1.0337 | 0.0110 | 0.0137 | 3 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 48 | hr | 3992 | 49 | 1.2207 | 1.0337 | 0.0123 | 0.0137 | 4 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 72 | hr | 3322 | 53 | 1.3617 | 1.2038 | 0.0160 | 0.0208 | 1 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 72 | hr | 3056 | 36 | 1.2580 | 1.2038 | 0.0118 | 0.0208 | 2 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 72 | hr | 2708 | 71 | 1.0984 | 1.2038 | 0.0262 | 0.0208 | 3 |
| AZ-628 | MZ7-mel | 0.0032 | uM | 72 | hr | 2713 | 79 | 1.0972 | 1.2038 | 0.0291 | 0.0208 | 4 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 24 | hr | 1600 | 25 | 1.1932 | 1.0178 | 0.0156 | 0.0129 | 1 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 24 | hr | 1519 | 17 | 1.1379 | 1.0178 | 0.0112 | 0.0129 | 2 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 24 | hr | 1280 | 16 | 0.9576 | 1.0178 | 0.0125 | 0.0129 | 3 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 24 | hr | 1046 | 13 | 0.7826 | 1.0178 | 0.0124 | 0.0129 | 4 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 48 | hr | 3353 | 71 | 1.0161 | 1.0431 | 0.0212 | 0.0171 | 1 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 48 | hr | 2925 | 57 | 0.8879 | 1.0431 | 0.0195 | 0.0171 | 2 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 48 | hr | 3741 | 47 | 1.1436 | 1.0431 | 0.0126 | 0.0171 | 3 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 48 | hr | 3689 | 56 | 1.1248 | 1.0431 | 0.0152 | 0.0171 | 4 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 72 | hr | 2767 | 35 | 1.1380 | 1.1122 | 0.0126 | 0.0145 | 1 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 72 | hr | 3098 | 38 | 1.2747 | 1.1122 | 0.0123 | 0.0145 | 2 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 72 | hr | 2577 | 49 | 1.0530 | 1.1122 | 0.0190 | 0.0145 | 3 |
| AZ-628 | MZ7-mel | 0.0100 | uM | 72 | hr | 2394 | 34 | 0.9831 | 1.1122 | 0.0142 | 0.0145 | 4 |
| AZ-628 | MZ7-mel | 0.0316 | uM | 24 | hr | 1659 | 10 | 1.2492 | 1.0498 | 0.0060 | 0.0104 | 1 |
| AZ-628 | MZ7-mel | 0.0316 | uM | 24 | hr | 1623 | 5 | 1.2258 | 1.0498 | 0.0031 | 0.0104 | 2 |
| AZ-628 | MZ7-mel | 0.0316 | uM | 24 | hr | 1038 | 11 | 0.7780 | 1.0498 | 0.0106 | 0.0104 | 3 |
| AZ-628 | MZ7-mel | 0.0316 | uM | 24 | hr | 1277 | 28 | 0.9462 | 1.0498 | 0.0219 | 0.0104 | 4 |
| AZ-628 | MZ7-mel | 0.0316 | uM | 48 | hr | 3492 | 62 | 1.0619 | 1.0012 | 0.0178 | 0.0173 | 1 |