Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib MMAC-SF 1.0000
uM
 48
hr
 3110 185 0.7711 0.7126 0.0595 0.0573 2
Vemurafenib MMAC-SF 1.0000
uM
 48
hr
 2640 139 0.6593 0.7126 0.0527 0.0573 3
Vemurafenib MMAC-SF 1.0000
uM
 48
hr
 3043 166 0.7585 0.7126 0.0546 0.0573 4
Vemurafenib MMAC-SF 1.0000
uM
 72
hr
 1336 368 0.2816 0.2904 0.2755 0.2648 1
Vemurafenib MMAC-SF 1.0000
uM
 72
hr
 1296 389 0.2639 0.2904 0.3002 0.2648 2
Vemurafenib MMAC-SF 1.0000
uM
 72
hr
 1393 353 0.3026 0.2904 0.2534 0.2648 3
Vemurafenib MMAC-SF 1.0000
uM
 72
hr
 1400 322 0.3136 0.2904 0.2300 0.2648 4
Vemurafenib MMAC-SF 3.1600
uM
 24
hr
 1
Vemurafenib MMAC-SF 3.1600
uM
 24
hr
 2
Vemurafenib MMAC-SF 3.1600
uM
 24
hr
 2157 114 0.7943 0.9055 0.0529 0.0553 3
Vemurafenib MMAC-SF 3.1600
uM
 24
hr
 2775 160 1.0167 0.9055 0.0577 0.0553 4
Vemurafenib MMAC-SF 3.1600
uM
 48
hr
 2173 213 0.5167 0.6035 0.0980 0.1218 1
Vemurafenib MMAC-SF 3.1600
uM
 48
hr
 3013 407 0.6870 0.6035 0.1351 0.1218 2
Vemurafenib MMAC-SF 3.1600
uM
 48
hr
 2525 264 0.5961 0.6035 0.1046 0.1218 3
Vemurafenib MMAC-SF 3.1600
uM
 48
hr
 2739 409 0.6142 0.6035 0.1493 0.1218 4
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 874 626 0.0721 0.0882 0.7163 0.6920 1
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 973 694 0.0812 0.0882 0.7133 0.6920 2
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 1123 713 0.1193 0.0882 0.6349 0.6920 3
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 931 655 0.0803 0.0882 0.7035 0.6920 4
MMAC-SF 0.0000
uM
 24
hr
 1
MMAC-SF 0.0000
uM
 24
hr
 1
MMAC-SF 0.0000
uM
 24
hr
 1
MMAC-SF 0.0000
uM
 24
hr
 1
MMAC-SF 0.0000
uM
 24
hr
 1
MMAC-SF 0.0000
uM
 24
hr
 1