Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib MMAC-SF 0.0100
uM
 24
hr
 2518 104 0.9385 0.8874 0.0413 0.0384 4
Vemurafenib MMAC-SF 0.0100
uM
 48
hr
 3268 140 0.8246 0.9235 0.0428 0.0447 1
Vemurafenib MMAC-SF 0.0100
uM
 48
hr
 2
Vemurafenib MMAC-SF 0.0100
uM
 48
hr
 3591 164 0.9034 0.9235 0.0457 0.0447 3
Vemurafenib MMAC-SF 0.0100
uM
 48
hr
 4143 189 1.0424 0.9235 0.0456 0.0447 4
Vemurafenib MMAC-SF 0.0100
uM
 72
hr
 3273 148 0.9091 0.9412 0.0452 0.0441 1
Vemurafenib MMAC-SF 0.0100
uM
 72
hr
 3305 150 0.9178 0.9412 0.0454 0.0441 2
Vemurafenib MMAC-SF 0.0100
uM
 72
hr
 3582 155 0.9970 0.9412 0.0433 0.0441 3
Vemurafenib MMAC-SF 0.0100
uM
 72
hr
 3377 143 0.9408 0.9412 0.0423 0.0441 4
Vemurafenib MMAC-SF 0.0316
uM
 24
hr
 1
Vemurafenib MMAC-SF 0.0316
uM
 24
hr
 2
Vemurafenib MMAC-SF 0.0316
uM
 24
hr
 2581 111 0.9603 0.9760 0.0430 0.0409 3
Vemurafenib MMAC-SF 0.0316
uM
 24
hr
 2654 103 0.9918 0.9760 0.0388 0.0409 4
Vemurafenib MMAC-SF 0.0316
uM
 48
hr
 3483 159 0.8763 0.9624 0.0457 0.0414 1
Vemurafenib MMAC-SF 0.0316
uM
 48
hr
 4177 157 1.0598 0.9624 0.0376 0.0414 2
Vemurafenib MMAC-SF 0.0316
uM
 48
hr
 3571 143 0.9037 0.9624 0.0400 0.0414 3
Vemurafenib MMAC-SF 0.0316
uM
 48
hr
 4001 170 1.0099 0.9624 0.0425 0.0414 4
Vemurafenib MMAC-SF 0.0316
uM
 72
hr
 3415 142 0.9522 0.9386 0.0416 0.0407 1
Vemurafenib MMAC-SF 0.0316
uM
 72
hr
 3412 130 0.9548 0.9386 0.0381 0.0407 2
Vemurafenib MMAC-SF 0.0316
uM
 72
hr
 3317 130 0.9271 0.9386 0.0392 0.0407 3
Vemurafenib MMAC-SF 0.0316
uM
 72
hr
 3308 145 0.9202 0.9386 0.0438 0.0407 4
Vemurafenib MMAC-SF 0.1000
uM
 24
hr
 1
Vemurafenib MMAC-SF 0.1000
uM
 24
hr
 2
Vemurafenib MMAC-SF 0.1000
uM
 24
hr
 2642 118 0.9813 1.0007 0.0447 0.0412 3
Vemurafenib MMAC-SF 0.1000
uM
 24
hr
 2727 103 1.0202 1.0007 0.0378 0.0412 4