Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | MMAC-SF | 0.0316 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 0.0316 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 0.0316 | uM | 24 | hr | 2737 | 97 | 1.0264 | 1.0219 | 0.0354 | 0.0349 | 3 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 24 | hr | 2710 | 93 | 1.0174 | 1.0219 | 0.0343 | 0.0349 | 4 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 48 | hr | 3703 | 160 | 0.9340 | 0.8800 | 0.0432 | 0.0469 | 1 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 48 | hr | 3576 | 175 | 0.8966 | 0.8800 | 0.0489 | 0.0469 | 2 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 48 | hr | 3312 | 170 | 0.8283 | 0.8800 | 0.0513 | 0.0469 | 3 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 48 | hr | 3417 | 151 | 0.8610 | 0.8800 | 0.0442 | 0.0469 | 4 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 72 | hr | 1785 | 55 | 0.5033 | 0.5628 | 0.0308 | 0.0318 | 1 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 72 | hr | 2132 | 69 | 0.6002 | 0.5628 | 0.0324 | 0.0318 | 2 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 72 | hr | 1886 | 56 | 0.5324 | 0.5628 | 0.0297 | 0.0318 | 3 |
| Selumetinib | MMAC-SF | 0.0316 | uM | 72 | hr | 2190 | 75 | 0.6153 | 0.5628 | 0.0342 | 0.0318 | 4 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 0.1000 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 0.1000 | uM | 24 | hr | 2759 | 115 | 1.0279 | 1.0468 | 0.0417 | 0.0436 | 3 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 24 | hr | 2872 | 131 | 1.0657 | 1.0468 | 0.0456 | 0.0436 | 4 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 48 | hr | 3175 | 172 | 0.7917 | 0.7432 | 0.0542 | 0.0518 | 1 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 48 | hr | 3179 | 158 | 0.7964 | 0.7432 | 0.0497 | 0.0518 | 2 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 48 | hr | 2718 | 155 | 0.6757 | 0.7432 | 0.0570 | 0.0518 | 3 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 48 | hr | 2819 | 130 | 0.7089 | 0.7432 | 0.0461 | 0.0518 | 4 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 72 | hr | 1459 | 96 | 0.3965 | 0.4491 | 0.0658 | 0.0807 | 1 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 72 | hr | 1871 | 107 | 0.5132 | 0.4491 | 0.0572 | 0.0807 | 2 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 72 | hr | 1583 | 160 | 0.4140 | 0.4491 | 0.1011 | 0.0807 | 3 |
| Selumetinib | MMAC-SF | 0.1000 | uM | 72 | hr | 1803 | 178 | 0.4727 | 0.4491 | 0.0987 | 0.0807 | 4 |
| Selumetinib | MMAC-SF | 0.3160 | uM | 24 | hr | 1 |