Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 MMAC-SF 0.3160
uM
 72
hr
 1558 348 0.3520 0.3668 0.2234 0.2255 3
AZ-628 MMAC-SF 0.3160
uM
 72
hr
 1821 442 0.4012 0.3668 0.2427 0.2255 4
AZ-628 MMAC-SF 1.0000
uM
 24
hr
 1
AZ-628 MMAC-SF 1.0000
uM
 24
hr
 2
AZ-628 MMAC-SF 1.0000
uM
 24
hr
 2733 131 1.0116 0.9996 0.0479 0.0524 3
AZ-628 MMAC-SF 1.0000
uM
 24
hr
 2693 153 0.9875 0.9996 0.0568 0.0524 4
AZ-628 MMAC-SF 1.0000
uM
 48
hr
 2969 439 0.6670 0.5596 0.1479 0.1586 1
AZ-628 MMAC-SF 1.0000
uM
 48
hr
 3006 395 0.6883 0.5596 0.1314 0.1586 2
AZ-628 MMAC-SF 1.0000
uM
 48
hr
 2735 464 0.5987 0.5596 0.1697 0.1586 3
AZ-628 MMAC-SF 1.0000
uM
 48
hr
 1325 246 0.2845 0.5596 0.1857 0.1586 4
AZ-628 MMAC-SF 1.0000
uM
 72
hr
 1337 611 0.2112 0.2232 0.4570 0.4650 1
AZ-628 MMAC-SF 1.0000
uM
 72
hr
 1455 663 0.2304 0.2232 0.4557 0.4650 2
AZ-628 MMAC-SF 1.0000
uM
 72
hr
 1402 675 0.2115 0.2232 0.4815 0.4650 3
AZ-628 MMAC-SF 1.0000
uM
 72
hr
 1543 719 0.2397 0.2232 0.4660 0.4650 4
AZ-628 MMAC-SF 3.1600
uM
 24
hr
 1
AZ-628 MMAC-SF 3.1600
uM
 24
hr
 2
AZ-628 MMAC-SF 3.1600
uM
 24
hr
 2834 166 1.0373 1.0340 0.0586 0.0606 3
AZ-628 MMAC-SF 3.1600
uM
 24
hr
 2828 177 1.0307 1.0340 0.0626 0.0606 4
AZ-628 MMAC-SF 3.1600
uM
 48
hr
 2764 636 0.5610 0.5172 0.2301 0.2496 1
AZ-628 MMAC-SF 3.1600
uM
 48
hr
 2683 672 0.5302 0.5172 0.2505 0.2496 2
AZ-628 MMAC-SF 3.1600
uM
 48
hr
 2354 580 0.4677 0.5172 0.2464 0.2496 3
AZ-628 MMAC-SF 3.1600
uM
 48
hr
 2656 721 0.5101 0.5172 0.2715 0.2496 4
AZ-628 MMAC-SF 3.1600
uM
 72
hr
 1164 698 0.1356 0.1411 0.5997 0.6202 1
AZ-628 MMAC-SF 3.1600
uM
 72
hr
 1228 739 0.1423 0.1411 0.6018 0.6202 2
AZ-628 MMAC-SF 3.1600
uM
 72
hr
 1481 953 0.1536 0.1411 0.6435 0.6202 3