Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 MMAC-SF 0.3160
uM
 24
hr
 2647 116 0.9840 0.9636 0.0438 0.0475 4
SB590885 MMAC-SF 0.3160
uM
 48
hr
 3372 175 0.8428 0.7906 0.0519 0.0567 1
SB590885 MMAC-SF 0.3160
uM
 48
hr
 3166 187 0.7853 0.7906 0.0591 0.0567 2
SB590885 MMAC-SF 0.3160
uM
 48
hr
 3
SB590885 MMAC-SF 0.3160
uM
 48
hr
 2998 177 0.7437 0.7906 0.0590 0.0567 4
SB590885 MMAC-SF 0.3160
uM
 72
hr
 1872 111 0.5123 0.5291 0.0593 0.0666 1
SB590885 MMAC-SF 0.3160
uM
 72
hr
 1924 139 0.5193 0.5291 0.0722 0.0666 2
SB590885 MMAC-SF 0.3160
uM
 72
hr
 1994 132 0.5417 0.5291 0.0662 0.0666 3
SB590885 MMAC-SF 0.3160
uM
 72
hr
 2005 138 0.5431 0.5291 0.0688 0.0666 4
SB590885 MMAC-SF 1.0000
uM
 24
hr
 1
SB590885 MMAC-SF 1.0000
uM
 24
hr
 2
SB590885 MMAC-SF 1.0000
uM
 24
hr
 2602 140 0.9572 0.9770 0.0538 0.0480 3
SB590885 MMAC-SF 1.0000
uM
 24
hr
 2677 113 0.9968 0.9770 0.0422 0.0480 4
SB590885 MMAC-SF 1.0000
uM
 48
hr
 3234 257 0.7848 0.7273 0.0795 0.0889 1
SB590885 MMAC-SF 1.0000
uM
 48
hr
 3161 278 0.7600 0.7273 0.0879 0.0889 2
SB590885 MMAC-SF 1.0000
uM
 48
hr
 2867 251 0.6896 0.7273 0.0875 0.0889 3
SB590885 MMAC-SF 1.0000
uM
 48
hr
 2846 286 0.6749 0.7273 0.1005 0.0889 4
SB590885 MMAC-SF 1.0000
uM
 72
hr
 1753 266 0.4326 0.4234 0.1517 0.1552 1
SB590885 MMAC-SF 1.0000
uM
 72
hr
 1696 253 0.4198 0.4234 0.1492 0.1552 2
SB590885 MMAC-SF 1.0000
uM
 72
hr
 1686 260 0.4148 0.4234 0.1542 0.1552 3
SB590885 MMAC-SF 1.0000
uM
 72
hr
 1756 291 0.4262 0.4234 0.1657 0.1552 4
SB590885 MMAC-SF 3.1600
uM
 24
hr
 1
SB590885 MMAC-SF 3.1600
uM
 24
hr
 2
SB590885 MMAC-SF 3.1600
uM
 24
hr
 2753 117 1.0248 1.0161 0.0425 0.0414 3
SB590885 MMAC-SF 3.1600
uM
 24
hr
 2700 109 1.0073 1.0161 0.0404 0.0414 4