Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 MMAC-SF 0.0316
uM
 24
hr
 2687 120 0.9980 0.9994 0.0447 0.0446 3
SB590885 MMAC-SF 0.0316
uM
 24
hr
 2694 120 1.0007 0.9994 0.0445 0.0446 4
SB590885 MMAC-SF 0.0316
uM
 48
hr
 3877 151 0.9823 0.9247 0.0389 0.0410 1
SB590885 MMAC-SF 0.0316
uM
 48
hr
 3681 124 0.9377 0.9247 0.0337 0.0410 2
SB590885 MMAC-SF 0.0316
uM
 48
hr
 3618 171 0.9087 0.9247 0.0473 0.0410 3
SB590885 MMAC-SF 0.0316
uM
 48
hr
 3453 152 0.8702 0.9247 0.0440 0.0410 4
SB590885 MMAC-SF 0.0316
uM
 72
hr
 2739 92 0.7700 0.7787 0.0336 0.0345 1
SB590885 MMAC-SF 0.0316
uM
 72
hr
 3040 120 0.8495 0.7787 0.0395 0.0345 2
SB590885 MMAC-SF 0.0316
uM
 72
hr
 2697 93 0.7575 0.7787 0.0345 0.0345 3
SB590885 MMAC-SF 0.0316
uM
 72
hr
 2616 80 0.7378 0.7787 0.0306 0.0345 4
SB590885 MMAC-SF 0.1000
uM
 24
hr
 1
SB590885 MMAC-SF 0.1000
uM
 24
hr
 2
SB590885 MMAC-SF 0.1000
uM
 24
hr
 2723 143 1.0031 1.0285 0.0525 0.0491 3
SB590885 MMAC-SF 0.1000
uM
 24
hr
 2841 130 1.0540 1.0285 0.0458 0.0491 4
SB590885 MMAC-SF 0.1000
uM
 48
hr
 3284 139 0.8291 0.7871 0.0423 0.0486 1
SB590885 MMAC-SF 0.1000
uM
 48
hr
 3230 156 0.8104 0.7871 0.0483 0.0486 2
SB590885 MMAC-SF 0.1000
uM
 48
hr
 3048 173 0.7579 0.7871 0.0568 0.0486 3
SB590885 MMAC-SF 0.1000
uM
 48
hr
 2988 140 0.7508 0.7871 0.0469 0.0486 4
SB590885 MMAC-SF 0.1000
uM
 72
hr
 2162 72 0.6080 0.5995 0.0333 0.0358 1
SB590885 MMAC-SF 0.1000
uM
 72
hr
 2035 65 0.5731 0.5995 0.0319 0.0358 2
SB590885 MMAC-SF 0.1000
uM
 72
hr
 2106 85 0.5879 0.5995 0.0404 0.0358 3
SB590885 MMAC-SF 0.1000
uM
 72
hr
 2246 84 0.6290 0.5995 0.0374 0.0358 4
SB590885 MMAC-SF 0.3160
uM
 24
hr
 1
SB590885 MMAC-SF 0.3160
uM
 24
hr
 2
SB590885 MMAC-SF 0.3160
uM
 24
hr
 2557 131 0.9432 0.9636 0.0512 0.0475 3