Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | LOXIMVI | 3.1600 | uM | 48 | hr | 1518 | 0.9554 | 1.1767 | 0.0639 | 0.0597 | 3 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 48 | hr | 2091 | 1.3265 | 1.1767 | 0.0564 | 0.0597 | 4 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 72 | hr | 1817 | 0.9890 | 1.2149 | 0.0963 | 0.1049 | 1 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 72 | hr | 2659 | 1.4709 | 1.2149 | 0.0816 | 0.1049 | 2 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 72 | hr | 1878 | 1.0017 | 1.2149 | 0.1145 | 0.1049 | 3 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 72 | hr | 2659 | 1.3980 | 1.2149 | 0.1271 | 0.1049 | 4 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 24 | hr | 2725 | 168 | 1.0442 | 0.9686 | 0.0617 | 0.0511 | 1 |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 24 | hr | 2526 | 123 | 0.9813 | 0.9686 | 0.0487 | 0.0511 | 2 |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 24 | hr | 2407 | 117 | 0.9352 | 0.9686 | 0.0486 | 0.0511 | 3 |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 24 | hr | 2345 | 107 | 0.9139 | 0.9686 | 0.0456 | 0.0511 | 4 |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 48 | hr | 1931 | 1.1826 | 1.0286 | 0.0891 | 0.1033 | 1 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 48 | hr | 1643 | 1.0004 | 1.0286 | 0.0943 | 0.1033 | 2 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 48 | hr | 1505 | 0.8727 | 1.0286 | 0.1375 | 0.1033 | 3 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 48 | hr | 1735 | 1.0589 | 1.0286 | 0.0922 | 0.1033 | 4 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 72 | hr | 3032 | 1.5552 | 1.5079 | 0.1484 | 0.1906 | 1 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 72 | hr | 2002 | 1.0125 | 1.5079 | 0.1603 | 0.1906 | 2 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 72 | hr | 3611 | 1.6534 | 1.5079 | 0.2398 | 0.1906 | 3 | |
| Vemurafenib | LOXIMVI | 0.0032 | uM | 72 | hr | 3824 | 1.8106 | 1.5079 | 0.2139 | 0.1906 | 4 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 24 | hr | 2727 | 186 | 1.0376 | 0.9398 | 0.0682 | 0.0524 | 1 |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 24 | hr | 3085 | 138 | 1.2034 | 0.9398 | 0.0447 | 0.0524 | 2 |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 24 | hr | 1963 | 89 | 0.7653 | 0.9398 | 0.0453 | 0.0524 | 3 |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 24 | hr | 1944 | 100 | 0.7530 | 0.9398 | 0.0514 | 0.0524 | 4 |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 48 | hr | 2931 | 1.8724 | 1.5828 | 0.0498 | 0.0517 | 1 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 48 | hr | 2682 | 1.7023 | 1.5828 | 0.0559 | 0.0517 | 2 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 48 | hr | 2098 | 1.3439 | 1.5828 | 0.0472 | 0.0517 | 3 |