Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | LOXIMVI | 0.3160 | uM | 48 | hr | 2278 | 1.4482 | 1.3293 | 0.0544 | 0.0582 | 2 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 48 | hr | 1729 | 1.0777 | 1.3293 | 0.0729 | 0.0582 | 3 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 48 | hr | 2644 | 1.6915 | 1.3293 | 0.0484 | 0.0582 | 4 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 72 | hr | 2157 | 1.2149 | 1.8061 | 0.0649 | 0.0604 | 1 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 72 | hr | 3720 | 2.1129 | 1.8061 | 0.0570 | 0.0604 | 2 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 72 | hr | 2904 | 1.6251 | 1.8061 | 0.0709 | 0.0604 | 3 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 72 | hr | 3964 | 2.2713 | 1.8061 | 0.0487 | 0.0604 | 4 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 24 | hr | 2879 | 103 | 1.1336 | 1.0012 | 0.0358 | 0.0476 | 1 |
| Selumetinib | LOXIMVI | 1.0000 | uM | 24 | hr | 2827 | 115 | 1.1075 | 1.0012 | 0.0407 | 0.0476 | 2 |
| Selumetinib | LOXIMVI | 1.0000 | uM | 24 | hr | 2396 | 115 | 0.9315 | 1.0012 | 0.0480 | 0.0476 | 3 |
| Selumetinib | LOXIMVI | 1.0000 | uM | 24 | hr | 2182 | 144 | 0.8322 | 1.0012 | 0.0660 | 0.0476 | 4 |
| Selumetinib | LOXIMVI | 1.0000 | uM | 48 | hr | 1956 | 1.2424 | 1.3318 | 0.0552 | 0.0523 | 1 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 48 | hr | 2692 | 1.7325 | 1.3318 | 0.0427 | 0.0523 | 2 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 48 | hr | 1488 | 0.9365 | 1.3318 | 0.0638 | 0.0523 | 3 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 48 | hr | 2211 | 1.4159 | 1.3318 | 0.0475 | 0.0523 | 4 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 72 | hr | 1713 | 0.9607 | 1.4510 | 0.0689 | 0.0759 | 1 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 72 | hr | 3041 | 1.7015 | 1.4510 | 0.0710 | 0.0759 | 2 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 72 | hr | 2429 | 1.3468 | 1.4510 | 0.0795 | 0.0759 | 3 | |
| Selumetinib | LOXIMVI | 1.0000 | uM | 72 | hr | 3254 | 1.7949 | 1.4510 | 0.0842 | 0.0759 | 4 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 24 | hr | 2537 | 141 | 0.9784 | 0.9128 | 0.0556 | 0.0428 | 1 |
| Selumetinib | LOXIMVI | 3.1600 | uM | 24 | hr | 2613 | 138 | 1.0107 | 0.9128 | 0.0528 | 0.0428 | 2 |
| Selumetinib | LOXIMVI | 3.1600 | uM | 24 | hr | 2119 | 74 | 0.8351 | 0.9128 | 0.0349 | 0.0428 | 3 |
| Selumetinib | LOXIMVI | 3.1600 | uM | 24 | hr | 2083 | 58 | 0.8269 | 0.9128 | 0.0278 | 0.0428 | 4 |
| Selumetinib | LOXIMVI | 3.1600 | uM | 48 | hr | 1655 | 1.0448 | 1.1767 | 0.0610 | 0.0597 | 1 | |
| Selumetinib | LOXIMVI | 3.1600 | uM | 48 | hr | 2178 | 1.3803 | 1.1767 | 0.0574 | 0.0597 | 2 |