Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1520 | 0.9412 | 1.2038 | 0.0789 | 0.0621 | 1 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 2605 | 1.6519 | 1.2038 | 0.0568 | 0.0621 | 2 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1628 | 1.0320 | 1.2038 | 0.0571 | 0.0621 | 3 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1874 | 1.1900 | 1.2038 | 0.0555 | 0.0621 | 4 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 72 | hr | 3145 | 1.8214 | 2.0428 | 0.0385 | 0.0426 | 1 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 72 | hr | 3562 | 2.0617 | 2.0428 | 0.0390 | 0.0426 | 2 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 72 | hr | 3172 | 1.8045 | 2.0428 | 0.0555 | 0.0426 | 3 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 72 | hr | 4284 | 2.4834 | 2.0428 | 0.0376 | 0.0426 | 4 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 24 | hr | 2998 | 137 | 1.1683 | 1.0652 | 0.0457 | 0.0452 | 1 |
| Selumetinib | LOXIMVI | 0.1000 | uM | 24 | hr | 3004 | 178 | 1.1540 | 1.0652 | 0.0593 | 0.0452 | 2 |
| Selumetinib | LOXIMVI | 0.1000 | uM | 24 | hr | 2641 | 121 | 1.0291 | 1.0652 | 0.0458 | 0.0452 | 3 |
| Selumetinib | LOXIMVI | 0.1000 | uM | 24 | hr | 2296 | 69 | 0.9094 | 1.0652 | 0.0301 | 0.0452 | 4 |
| Selumetinib | LOXIMVI | 0.1000 | uM | 48 | hr | 1392 | 0.8485 | 1.2713 | 0.0934 | 0.0589 | 1 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 48 | hr | 2674 | 1.7332 | 1.2713 | 0.0359 | 0.0589 | 2 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 48 | hr | 1526 | 0.9668 | 1.2713 | 0.0577 | 0.0589 | 3 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 48 | hr | 2403 | 1.5369 | 1.2713 | 0.0487 | 0.0589 | 4 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 72 | hr | 2122 | 1.2137 | 1.8648 | 0.0504 | 0.0445 | 1 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 72 | hr | 3852 | 2.2304 | 1.8648 | 0.0387 | 0.0445 | 2 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 72 | hr | 2816 | 1.6076 | 1.8648 | 0.0522 | 0.0445 | 3 | |
| Selumetinib | LOXIMVI | 0.1000 | uM | 72 | hr | 4149 | 2.4075 | 1.8648 | 0.0366 | 0.0445 | 4 | |
| Selumetinib | LOXIMVI | 0.3160 | uM | 24 | hr | 2938 | 110 | 1.1548 | 0.9805 | 0.0374 | 0.0393 | 1 |
| Selumetinib | LOXIMVI | 0.3160 | uM | 24 | hr | 2730 | 109 | 1.0703 | 0.9805 | 0.0399 | 0.0393 | 2 |
| Selumetinib | LOXIMVI | 0.3160 | uM | 24 | hr | 2256 | 86 | 0.8861 | 0.9805 | 0.0381 | 0.0393 | 3 |
| Selumetinib | LOXIMVI | 0.3160 | uM | 24 | hr | 2071 | 86 | 0.8106 | 0.9805 | 0.0415 | 0.0393 | 4 |
| Selumetinib | LOXIMVI | 0.3160 | uM | 48 | hr | 1735 | 1.0999 | 1.3293 | 0.0571 | 0.0582 | 1 |