Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | LOXIMVI | 0.1000 | uM | 24 | hr | 2814 | 183 | 1.0744 | 0.9424 | 0.0650 | 0.0586 | 2 |
| AZ-628 | LOXIMVI | 0.1000 | uM | 24 | hr | 2058 | 108 | 0.7963 | 0.9424 | 0.0525 | 0.0586 | 3 |
| AZ-628 | LOXIMVI | 0.1000 | uM | 24 | hr | 2214 | 126 | 0.8527 | 0.9424 | 0.0569 | 0.0586 | 4 |
| AZ-628 | LOXIMVI | 0.1000 | uM | 48 | hr | 2278 | 1.4623 | 1.4717 | 0.0452 | 0.0479 | 1 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 48 | hr | 2361 | 1.5140 | 1.4717 | 0.0462 | 0.0479 | 2 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 48 | hr | 2253 | 1.4374 | 1.4717 | 0.0510 | 0.0479 | 3 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 48 | hr | 2304 | 1.4730 | 1.4717 | 0.0490 | 0.0479 | 4 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 72 | hr | 2825 | 1.5829 | 1.5508 | 0.0697 | 0.0836 | 1 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 72 | hr | 2977 | 1.6467 | 1.5508 | 0.0816 | 0.0836 | 2 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 72 | hr | 2606 | 1.4094 | 1.5508 | 0.1021 | 0.0836 | 3 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 72 | hr | 2826 | 1.5642 | 1.5508 | 0.0810 | 0.0836 | 4 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 24 | hr | 2298 | 53 | 0.9168 | 0.8604 | 0.0231 | 0.0296 | 1 |
| AZ-628 | LOXIMVI | 0.3160 | uM | 24 | hr | 2564 | 73 | 1.0172 | 0.8604 | 0.0285 | 0.0296 | 2 |
| AZ-628 | LOXIMVI | 0.3160 | uM | 24 | hr | 1959 | 74 | 0.7698 | 0.8604 | 0.0378 | 0.0296 | 3 |
| AZ-628 | LOXIMVI | 0.3160 | uM | 24 | hr | 1861 | 54 | 0.7379 | 0.8604 | 0.0290 | 0.0296 | 4 |
| AZ-628 | LOXIMVI | 0.3160 | uM | 48 | hr | 2052 | 1.2861 | 1.3673 | 0.0677 | 0.0630 | 1 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 48 | hr | 2052 | 1.2868 | 1.3673 | 0.0673 | 0.0630 | 2 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 48 | hr | 2235 | 1.4199 | 1.3673 | 0.0550 | 0.0630 | 3 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 48 | hr | 2341 | 1.4764 | 1.3673 | 0.0619 | 0.0630 | 4 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 72 | hr | 2385 | 1.2823 | 1.3006 | 0.1073 | 0.1173 | 1 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 72 | hr | 2369 | 1.2594 | 1.3006 | 0.1174 | 0.1173 | 2 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 72 | hr | 2612 | 1.3908 | 1.3006 | 0.1160 | 0.1173 | 3 | |
| AZ-628 | LOXIMVI | 0.3160 | uM | 72 | hr | 2419 | 1.2697 | 1.3006 | 0.1286 | 0.1173 | 4 | |
| AZ-628 | LOXIMVI | 1.0000 | uM | 24 | hr | 2518 | 205 | 0.9445 | 0.8617 | 0.0814 | 0.0677 | 1 |
| AZ-628 | LOXIMVI | 1.0000 | uM | 24 | hr | 2472 | 111 | 0.9641 | 0.8617 | 0.0449 | 0.0677 | 2 |