Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | LOXIMVI | 0.0100 | uM | 24 | hr | 2915 | 133 | 1.1361 | 0.9488 | 0.0456 | 0.0347 | 1 |
| AZ-628 | LOXIMVI | 0.0100 | uM | 24 | hr | 2866 | 134 | 1.1156 | 0.9488 | 0.0468 | 0.0347 | 2 |
| AZ-628 | LOXIMVI | 0.0100 | uM | 24 | hr | 1782 | 33 | 0.7142 | 0.9488 | 0.0185 | 0.0347 | 3 |
| AZ-628 | LOXIMVI | 0.0100 | uM | 24 | hr | 2089 | 58 | 0.8294 | 0.9488 | 0.0278 | 0.0347 | 4 |
| AZ-628 | LOXIMVI | 0.0100 | uM | 48 | hr | 2145 | 1.3386 | 1.4767 | 0.0718 | 0.0536 | 1 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 48 | hr | 2532 | 1.6162 | 1.4767 | 0.0506 | 0.0536 | 2 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 48 | hr | 2188 | 1.4018 | 1.4767 | 0.0471 | 0.0536 | 3 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 48 | hr | 2415 | 1.5503 | 1.4767 | 0.0451 | 0.0536 | 4 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 72 | hr | 2386 | 1.2070 | 1.9518 | 0.1601 | 0.1045 | 1 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 72 | hr | 3245 | 1.6431 | 1.9518 | 0.1593 | 0.1045 | 2 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 72 | hr | 3930 | 2.2623 | 1.9518 | 0.0443 | 0.1045 | 3 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 72 | hr | 4731 | 2.6948 | 1.9518 | 0.0543 | 0.1045 | 4 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 24 | hr | 2823 | 108 | 1.1087 | 0.9559 | 0.0383 | 0.0365 | 1 |
| AZ-628 | LOXIMVI | 0.0316 | uM | 24 | hr | 2773 | 126 | 1.0809 | 0.9559 | 0.0454 | 0.0365 | 2 |
| AZ-628 | LOXIMVI | 0.0316 | uM | 24 | hr | 2133 | 69 | 0.8429 | 0.9559 | 0.0323 | 0.0365 | 3 |
| AZ-628 | LOXIMVI | 0.0316 | uM | 24 | hr | 1997 | 60 | 0.7910 | 0.9559 | 0.0300 | 0.0365 | 4 |
| AZ-628 | LOXIMVI | 0.0316 | uM | 48 | hr | 2541 | 1.6478 | 1.5915 | 0.0354 | 0.0416 | 1 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 48 | hr | 2862 | 1.8448 | 1.5915 | 0.0412 | 0.0416 | 2 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 48 | hr | 2280 | 1.4603 | 1.5915 | 0.0474 | 0.0416 | 3 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 48 | hr | 2195 | 1.4132 | 1.5915 | 0.0424 | 0.0416 | 4 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 72 | hr | 3180 | 1.8467 | 2.1825 | 0.0358 | 0.0405 | 1 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 72 | hr | 3461 | 2.0039 | 2.1825 | 0.0387 | 0.0405 | 2 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 72 | hr | 3903 | 2.2503 | 2.1825 | 0.0428 | 0.0405 | 3 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 72 | hr | 4569 | 2.6291 | 2.1825 | 0.0446 | 0.0405 | 4 | |
| AZ-628 | LOXIMVI | 0.1000 | uM | 24 | hr | 2726 | 164 | 1.0462 | 0.9424 | 0.0602 | 0.0586 | 1 |