Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | LOXIMVI | 0.3160 | uM | 48 | hr | 3724 | 2.3988 | 2.2627 | 0.0419 | 0.0374 | 4 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5438 | 3.1375 | 2.9681 | 0.0421 | 0.0478 | 1 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5369 | 3.1019 | 2.9681 | 0.0408 | 0.0478 | 2 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5374 | 3.1266 | 2.9681 | 0.0341 | 0.0478 | 3 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 4494 | 2.5062 | 2.9681 | 0.0741 | 0.0478 | 4 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 24 | hr | 2763 | 97 | 1.0887 | 0.9870 | 0.0351 | 0.0511 | 1 |
| SB590885 | LOXIMVI | 1.0000 | uM | 24 | hr | 2935 | 185 | 1.1230 | 0.9870 | 0.0630 | 0.0511 | 2 |
| SB590885 | LOXIMVI | 1.0000 | uM | 24 | hr | 2236 | 97 | 0.8735 | 0.9870 | 0.0434 | 0.0511 | 3 |
| SB590885 | LOXIMVI | 1.0000 | uM | 24 | hr | 2255 | 142 | 0.8629 | 0.9870 | 0.0630 | 0.0511 | 4 |
| SB590885 | LOXIMVI | 1.0000 | uM | 48 | hr | 2500 | 1.6021 | 1.8331 | 0.0468 | 0.0404 | 1 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 48 | hr | 2754 | 1.7850 | 1.8331 | 0.0359 | 0.0404 | 2 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 48 | hr | 3066 | 1.9793 | 1.8331 | 0.0398 | 0.0404 | 3 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 48 | hr | 3043 | 1.9658 | 1.8331 | 0.0391 | 0.0404 | 4 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 72 | hr | 4191 | 2.4111 | 2.3305 | 0.0449 | 0.0458 | 1 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 72 | hr | 4727 | 2.7267 | 2.3305 | 0.0423 | 0.0458 | 2 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 72 | hr | 3392 | 1.9545 | 2.3305 | 0.0433 | 0.0458 | 3 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 72 | hr | 3908 | 2.2298 | 2.3305 | 0.0527 | 0.0458 | 4 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 24 | hr | 2595 | 81 | 1.0266 | 0.9032 | 0.0312 | 0.0461 | 1 |
| SB590885 | LOXIMVI | 3.1600 | uM | 24 | hr | 2519 | 150 | 0.9674 | 0.9032 | 0.0595 | 0.0461 | 2 |
| SB590885 | LOXIMVI | 3.1600 | uM | 24 | hr | 2174 | 108 | 0.8437 | 0.9032 | 0.0497 | 0.0461 | 3 |
| SB590885 | LOXIMVI | 3.1600 | uM | 24 | hr | 1985 | 87 | 0.7751 | 0.9032 | 0.0438 | 0.0461 | 4 |
| SB590885 | LOXIMVI | 3.1600 | uM | 48 | hr | 2272 | 1.4542 | 1.4719 | 0.0480 | 0.0453 | 1 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 48 | hr | 2104 | 1.3480 | 1.4719 | 0.0471 | 0.0453 | 2 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 48 | hr | 2365 | 1.5154 | 1.4719 | 0.0469 | 0.0453 | 3 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 48 | hr | 2430 | 1.5698 | 1.4719 | 0.0391 | 0.0453 | 4 |