Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | C32 | 0.1000 | uM | 24 | hr | 2243 | 538 | 0.9858 | 1.0212 | 0.2399 | 0.2261 | 2 |
| AZ-628 | C32 | 0.1000 | uM | 48 | hr | 2071 | 426 | 0.8004 | 0.7935 | 0.2057 | 0.2126 | 1 |
| AZ-628 | C32 | 0.1000 | uM | 48 | hr | 1859 | 443 | 0.6890 | 0.7935 | 0.2383 | 0.2126 | 2 |
| AZ-628 | C32 | 0.1000 | uM | 48 | hr | 2176 | 434 | 0.8476 | 0.7935 | 0.1995 | 0.2126 | 4 |
| AZ-628 | C32 | 0.1000 | uM | 72 | hr | 1469 | 477 | 0.4331 | 0.4501 | 0.3247 | 0.3008 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 24 | hr | 2282 | 195 | 1.2066 | 1.0868 | 0.0855 | 0.0886 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 24 | hr | 2319 | 203 | 1.2234 | 1.0868 | 0.0875 | 0.0886 | 2 |
| AZ-628 | C32 | 0.0032 | uM | 24 | hr | 1864 | 166 | 0.9817 | 1.0868 | 0.0891 | 0.0886 | 4 |
| AZ-628 | C32 | 0.0032 | uM | 48 | hr | 2574 | 263 | 1.1245 | 1.1683 | 0.1022 | 0.0865 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 48 | hr | 2721 | 210 | 1.2218 | 1.1683 | 0.0772 | 0.0865 | 4 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 1962 | 179 | 0.7785 | 0.9919 | 0.0912 | 0.0829 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 2977 | 256 | 1.1880 | 0.9919 | 0.0860 | 0.0829 | 3 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 2725 | 207 | 1.0994 | 0.9919 | 0.0760 | 0.0829 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 24 | hr | 2228 | 301 | 1.1141 | 1.1216 | 0.1351 | 0.1277 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 2389 | 230 | 1.0505 | 1.1445 | 0.0963 | 0.1033 | 1 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 3067 | 264 | 1.3639 | 1.1445 | 0.0861 | 0.1033 | 3 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 2815 | 294 | 1.2267 | 1.1445 | 0.1044 | 0.1033 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2925 | 134 | 1.2186 | 1.0955 | 0.0458 | 0.0581 | 3 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2708 | 182 | 1.1029 | 1.0955 | 0.0672 | 0.0581 | 4 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 1858 | 443 | 0.8181 | 1.0452 | 0.2384 | 0.1770 | 2 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 2345 | 340 | 1.1592 | 1.0452 | 0.1450 | 0.1770 | 3 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2416 | 175 | 1.0904 | 1.0132 | 0.0724 | 0.0851 | 4 |
| AZ-628 | C32 | 0.0316 | uM | 72 | hr | 2113 | 80 | 0.8876 | 0.9467 | 0.0379 | 0.0379 | 1 |
| AZ-628 | C32 | 0.3160 | uM | 24 | hr | 2238 | 618 | 0.9366 | 0.8698 | 0.2761 | 0.2799 | 2 |
| AZ-628 | C32 | 0.3160 | uM | 24 | hr | 2067 | 597 | 0.8499 | 0.8698 | 0.2888 | 0.2799 | 1 |