Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib WM1552C 0.3160
uM
 72
hr
 3155 340 0.5460 0.5260 0.1078 0.1044 2
Selumetinib WM1552C 0.3160
uM
 72
hr
 2975 331 0.5128 0.5260 0.1113 0.1044 3
Selumetinib WM1552C 0.3160
uM
 72
hr
 2882 301 0.5006 0.5260 0.1044 0.1044 4
Selumetinib WM1552C 1.0000
uM
 24
hr
 2955 335 1.0457 1.0611 0.1134 0.1116 1
Selumetinib WM1552C 1.0000
uM
 24
hr
 3030 333 1.0764 1.0611 0.1099 0.1116 2
Selumetinib WM1552C 1.0000
uM
 24
hr
 3
Selumetinib WM1552C 1.0000
uM
 24
hr
 4
Selumetinib WM1552C 1.0000
uM
 48
hr
 2414 211 0.7008 0.6759 0.0874 0.0765 1
Selumetinib WM1552C 1.0000
uM
 48
hr
 2327 157 0.6903 0.6759 0.0675 0.0765 2
Selumetinib WM1552C 1.0000
uM
 48
hr
 2155 111 0.6502 0.6759 0.0515 0.0765 3
Selumetinib WM1552C 1.0000
uM
 48
hr
 2312 230 0.6623 0.6759 0.0995 0.0765 4
Selumetinib WM1552C 1.0000
uM
 72
hr
 2803 392 0.4676 0.4405 0.1399 0.1455 1
Selumetinib WM1552C 1.0000
uM
 72
hr
 2855 403 0.4756 0.4405 0.1412 0.1455 2
Selumetinib WM1552C 1.0000
uM
 72
hr
 2394 350 0.3965 0.4405 0.1462 0.1455 3
Selumetinib WM1552C 1.0000
uM
 72
hr
 2576 399 0.4223 0.4405 0.1549 0.1455 4
Selumetinib WM1552C 3.1600
uM
 24
hr
 2532 218 0.9236 0.9471 0.0861 0.0803 1
Selumetinib WM1552C 3.1600
uM
 24
hr
 2628 196 0.9707 0.9471 0.0746 0.0803 2
Selumetinib WM1552C 3.1600
uM
 24
hr
 3
Selumetinib WM1552C 3.1600
uM
 24
hr
 4
Selumetinib WM1552C 3.1600
uM
 48
hr
 2340 215 0.6760 0.6774 0.0919 0.1003 1
Selumetinib WM1552C 3.1600
uM
 48
hr
 2400 176 0.7075 0.6774 0.0733 0.1003 2
Selumetinib WM1552C 3.1600
uM
 48
hr
 2462 274 0.6960 0.6774 0.1113 0.1003 3
Selumetinib WM1552C 3.1600
uM
 48
hr
 2263 282 0.6302 0.6774 0.1246 0.1003 4
Selumetinib WM1552C 3.1600
uM
 72
hr
 2925 578 0.4552 0.4106 0.1976 0.1902 1
Selumetinib WM1552C 3.1600
uM
 72
hr
 2940 569 0.4599 0.4106 0.1935 0.1902 2