Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib WM1552C 0.0316
uM
 72
hr
 4170 294 0.7518 0.8060 0.0705 0.0737 1
Selumetinib WM1552C 0.0316
uM
 72
hr
 5289 427 0.9431 0.8060 0.0807 0.0737 2
Selumetinib WM1552C 0.0316
uM
 72
hr
 4291 306 0.7729 0.8060 0.0713 0.0737 3
Selumetinib WM1552C 0.0316
uM
 72
hr
 4201 303 0.7561 0.8060 0.0721 0.0737 4
Selumetinib WM1552C 0.1000
uM
 24
hr
 2951 255 1.0760 1.0696 0.0864 0.0894 1
Selumetinib WM1552C 0.1000
uM
 24
hr
 2935 271 1.0632 1.0696 0.0923 0.0894 2
Selumetinib WM1552C 0.1000
uM
 24
hr
 3
Selumetinib WM1552C 0.1000
uM
 24
hr
 4
Selumetinib WM1552C 0.1000
uM
 48
hr
 2961 191 0.8811 0.8675 0.0645 0.0656 1
Selumetinib WM1552C 0.1000
uM
 48
hr
 2840 154 0.8544 0.8675 0.0542 0.0656 2
Selumetinib WM1552C 0.1000
uM
 48
hr
 2806 195 0.8306 0.8675 0.0695 0.0656 3
Selumetinib WM1552C 0.1000
uM
 48
hr
 3069 228 0.9037 0.8675 0.0743 0.0656 4
Selumetinib WM1552C 0.1000
uM
 72
hr
 3567 311 0.6315 0.6347 0.0872 0.0814 1
Selumetinib WM1552C 0.1000
uM
 72
hr
 4093 333 0.7293 0.6347 0.0814 0.0814 2
Selumetinib WM1552C 0.1000
uM
 72
hr
 2935 222 0.5262 0.6347 0.0756 0.0814 3
Selumetinib WM1552C 0.1000
uM
 72
hr
 3656 297 0.6515 0.6347 0.0812 0.0814 4
Selumetinib WM1552C 0.3160
uM
 24
hr
 2785 236 1.0173 1.0289 0.0847 0.0876 1
Selumetinib WM1552C 0.3160
uM
 24
hr
 2866 259 1.0405 1.0289 0.0904 0.0876 2
Selumetinib WM1552C 0.3160
uM
 24
hr
 3
Selumetinib WM1552C 0.3160
uM
 24
hr
 4
Selumetinib WM1552C 0.3160
uM
 48
hr
 2627 221 0.7654 0.7611 0.0841 0.0753 1
Selumetinib WM1552C 0.3160
uM
 48
hr
 2662 164 0.7946 0.7611 0.0616 0.0753 2
Selumetinib WM1552C 0.3160
uM
 48
hr
 2374 162 0.7036 0.7611 0.0682 0.0753 3
Selumetinib WM1552C 0.3160
uM
 48
hr
 2688 234 0.7806 0.7611 0.0871 0.0753 4
Selumetinib WM1552C 0.3160
uM
 72
hr
 3099 292 0.5445 0.5260 0.0942 0.1044 1