Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | RVH-421 | 3.1600 | uM | 24 | hr | 3 | ||||||
| AZ-628 | RVH-421 | 3.1600 | uM | 24 | hr | 4 | ||||||
| AZ-628 | RVH-421 | 3.1600 | uM | 48 | hr | 1148 | 145 | 0.5241 | 0.5441 | 0.1263 | 0.1082 | 1 |
| AZ-628 | RVH-421 | 3.1600 | uM | 48 | hr | 1237 | 133 | 0.5768 | 0.5441 | 0.1075 | 0.1082 | 2 |
| AZ-628 | RVH-421 | 3.1600 | uM | 48 | hr | 1112 | 103 | 0.5272 | 0.5441 | 0.0926 | 0.1082 | 3 |
| AZ-628 | RVH-421 | 3.1600 | uM | 48 | hr | 1174 | 125 | 0.5481 | 0.5441 | 0.1065 | 0.1082 | 4 |
| AZ-628 | RVH-421 | 3.1600 | uM | 72 | hr | 3525 | 660 | 0.3283 | 0.4118 | 0.1872 | 0.1648 | 1 |
| AZ-628 | RVH-421 | 3.1600 | uM | 72 | hr | 4754 | 783 | 0.4550 | 0.4118 | 0.1647 | 0.1648 | 2 |
| AZ-628 | RVH-421 | 3.1600 | uM | 72 | hr | 3884 | 592 | 0.3772 | 0.4118 | 0.1524 | 0.1648 | 3 |
| AZ-628 | RVH-421 | 3.1600 | uM | 72 | hr | 5025 | 778 | 0.4867 | 0.4118 | 0.1548 | 0.1648 | 4 |
| Selumetinib | RVH-421 | 0.0032 | uM | 24 | hr | 1481 | 87 | 1.0085 | 0.9752 | 0.0587 | 0.0531 | 1 |
| Selumetinib | RVH-421 | 0.0032 | uM | 24 | hr | 1367 | 65 | 0.9419 | 0.9752 | 0.0475 | 0.0531 | 2 |
| Selumetinib | RVH-421 | 0.0032 | uM | 24 | hr | 3 | ||||||
| Selumetinib | RVH-421 | 0.0032 | uM | 24 | hr | 4 | ||||||
| Selumetinib | RVH-421 | 0.0032 | uM | 48 | hr | 2213 | 108 | 1.0999 | 1.0391 | 0.0488 | 0.0489 | 1 |
| Selumetinib | RVH-421 | 0.0032 | uM | 48 | hr | 2142 | 95 | 1.0696 | 1.0391 | 0.0444 | 0.0489 | 2 |
| Selumetinib | RVH-421 | 0.0032 | uM | 48 | hr | 1952 | 99 | 0.9682 | 1.0391 | 0.0507 | 0.0489 | 3 |
| Selumetinib | RVH-421 | 0.0032 | uM | 48 | hr | 2056 | 106 | 1.0189 | 1.0391 | 0.0516 | 0.0489 | 4 |
| Selumetinib | RVH-421 | 0.0032 | uM | 72 | hr | 9255 | 282 | 1.0282 | 1.0141 | 0.0305 | 0.0328 | 1 |
| Selumetinib | RVH-421 | 0.0032 | uM | 72 | hr | 9411 | 281 | 1.0462 | 1.0141 | 0.0299 | 0.0328 | 2 |
| Selumetinib | RVH-421 | 0.0032 | uM | 72 | hr | 8393 | 292 | 0.9283 | 1.0141 | 0.0348 | 0.0328 | 3 |
| Selumetinib | RVH-421 | 0.0032 | uM | 72 | hr | 9540 | 343 | 1.0539 | 1.0141 | 0.0360 | 0.0328 | 4 |
| Selumetinib | RVH-421 | 0.0100 | uM | 24 | hr | 1462 | 68 | 1.0085 | 0.9947 | 0.0465 | 0.0501 | 1 |
| Selumetinib | RVH-421 | 0.0100 | uM | 24 | hr | 1433 | 77 | 0.9810 | 0.9947 | 0.0537 | 0.0501 | 2 |
| Selumetinib | RVH-421 | 0.0100 | uM | 24 | hr | 3 |