Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | COLO 858 | 3.1600 | uM | 48 | hr | 1954 | 775 | 0.2694 | 0.2483 | 0.3966 | 0.4355 | 3 |
| AZ-628 | COLO 858 | 3.1600 | uM | 48 | hr | 1997 | 841 | 0.2641 | 0.2483 | 0.4211 | 0.4355 | 4 |
| AZ-628 | COLO 858 | 3.1600 | uM | 72 | hr | 1255 | 678 | 0.2096 | 0.2130 | 0.5402 | 0.5342 | 1 |
| AZ-628 | COLO 858 | 3.1600 | uM | 72 | hr | 1302 | 717 | 0.2125 | 0.2130 | 0.5507 | 0.5342 | 2 |
| AZ-628 | COLO 858 | 3.1600 | uM | 72 | hr | 1241 | 657 | 0.2121 | 0.2130 | 0.5294 | 0.5342 | 3 |
| AZ-628 | COLO 858 | 3.1600 | uM | 72 | hr | 1241 | 641 | 0.2179 | 0.2130 | 0.5165 | 0.5342 | 4 |
| Selumetinib | COLO 858 | 0.0032 | uM | 24 | hr | 3795 | 209 | 1.1979 | 0.8441 | 0.0551 | 0.0501 | 1 |
| Selumetinib | COLO 858 | 0.0032 | uM | 24 | hr | 3790 | 188 | 1.2032 | 0.8441 | 0.0496 | 0.0501 | 2 |
| Selumetinib | COLO 858 | 0.0032 | uM | 24 | hr | 1482 | 67 | 0.4727 | 0.8441 | 0.0452 | 0.0501 | 3 |
| Selumetinib | COLO 858 | 0.0032 | uM | 24 | hr | 1585 | 80 | 0.5027 | 0.8441 | 0.0505 | 0.0501 | 4 |
| Selumetinib | COLO 858 | 0.0032 | uM | 48 | hr | 4621 | 227 | 1.0040 | 0.9832 | 0.0491 | 0.0496 | 1 |
| Selumetinib | COLO 858 | 0.0032 | uM | 48 | hr | 4385 | 199 | 0.9564 | 0.9832 | 0.0454 | 0.0496 | 2 |
| Selumetinib | COLO 858 | 0.0032 | uM | 48 | hr | 4578 | 248 | 0.9893 | 0.9832 | 0.0542 | 0.0496 | 3 |
| Selumetinib | COLO 858 | 0.0032 | uM | 48 | hr | 4 | ||||||
| Selumetinib | COLO 858 | 0.0032 | uM | 72 | hr | 2909 | 249 | 0.9662 | 0.9742 | 0.0856 | 0.0958 | 1 |
| Selumetinib | COLO 858 | 0.0032 | uM | 72 | hr | 3191 | 347 | 1.0330 | 0.9742 | 0.1087 | 0.0958 | 2 |
| Selumetinib | COLO 858 | 0.0032 | uM | 72 | hr | 2790 | 254 | 0.9212 | 0.9742 | 0.0910 | 0.0958 | 3 |
| Selumetinib | COLO 858 | 0.0032 | uM | 72 | hr | 2980 | 292 | 0.9764 | 0.9742 | 0.0980 | 0.0958 | 4 |
| Selumetinib | COLO 858 | 0.0100 | uM | 24 | hr | 4107 | 175 | 1.3134 | 1.0900 | 0.0426 | 0.0441 | 1 |
| Selumetinib | COLO 858 | 0.0100 | uM | 24 | hr | 4142 | 196 | 1.3181 | 1.0900 | 0.0473 | 0.0441 | 2 |
| Selumetinib | COLO 858 | 0.0100 | uM | 24 | hr | 2632 | 117 | 0.8401 | 1.0900 | 0.0445 | 0.0441 | 3 |
| Selumetinib | COLO 858 | 0.0100 | uM | 24 | hr | 2776 | 117 | 0.8882 | 1.0900 | 0.0421 | 0.0441 | 4 |
| Selumetinib | COLO 858 | 0.0100 | uM | 48 | hr | 4712 | 253 | 1.0188 | 1.0530 | 0.0537 | 0.0490 | 1 |
| Selumetinib | COLO 858 | 0.0100 | uM | 48 | hr | 4869 | 226 | 1.0609 | 1.0530 | 0.0464 | 0.0490 | 2 |
| Selumetinib | COLO 858 | 0.0100 | uM | 48 | hr | 4978 | 267 | 1.0764 | 1.0530 | 0.0536 | 0.0490 | 3 |