Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib WM1552C 0.0032
uM
 48
hr
 3050 210 0.9034 0.9467 0.0689 0.0650 4
Selumetinib WM1552C 0.0032
uM
 72
hr
 3517 312 0.6217 0.8615 0.0887 0.0885 1
Selumetinib WM1552C 0.0032
uM
 72
hr
 6015 463 1.0769 0.8615 0.0770 0.0885 2
Selumetinib WM1552C 0.0032
uM
 72
hr
 4666 450 0.8178 0.8615 0.0964 0.0885 3
Selumetinib WM1552C 0.0032
uM
 72
hr
 5280 486 0.9299 0.8615 0.0920 0.0885 4
Selumetinib WM1552C 0.0100
uM
 24
hr
 2733 202 1.0102 0.9932 0.0739 0.0689 1
Selumetinib WM1552C 0.0100
uM
 24
hr
 2613 167 0.9762 0.9932 0.0639 0.0689 2
Selumetinib WM1552C 0.0100
uM
 24
hr
 3
Selumetinib WM1552C 0.0100
uM
 24
hr
 4
Selumetinib WM1552C 0.0100
uM
 48
hr
 3450 220 1.0275 0.9916 0.0638 0.0655 1
Selumetinib WM1552C 0.0100
uM
 48
hr
 3401 212 1.0144 0.9916 0.0623 0.0655 2
Selumetinib WM1552C 0.0100
uM
 48
hr
 3200 204 0.9530 0.9916 0.0638 0.0655 3
Selumetinib WM1552C 0.0100
uM
 48
hr
 3292 238 0.9715 0.9916 0.0723 0.0655 4
Selumetinib WM1552C 0.0100
uM
 72
hr
 4625 359 0.8275 0.9176 0.0776 0.0730 1
Selumetinib WM1552C 0.0100
uM
 72
hr
 5962 368 1.0850 0.9176 0.0617 0.0730 2
Selumetinib WM1552C 0.0100
uM
 72
hr
 4642 359 0.8307 0.9176 0.0773 0.0730 3
Selumetinib WM1552C 0.0100
uM
 72
hr
 5170 390 0.9271 0.9176 0.0754 0.0730 4
Selumetinib WM1552C 0.0316
uM
 24
hr
 2947 234 1.0828 1.0822 0.0794 0.0771 1
Selumetinib WM1552C 0.0316
uM
 24
hr
 2929 219 1.0816 1.0822 0.0748 0.0771 2
Selumetinib WM1552C 0.0316
uM
 24
hr
 3
Selumetinib WM1552C 0.0316
uM
 24
hr
 4
Selumetinib WM1552C 0.0316
uM
 48
hr
 3250 155 0.9845 0.9558 0.0477 0.0575 1
Selumetinib WM1552C 0.0316
uM
 48
hr
 3188 195 0.9521 0.9558 0.0612 0.0575 2
Selumetinib WM1552C 0.0316
uM
 48
hr
 3090 182 0.9250 0.9558 0.0589 0.0575 3
Selumetinib WM1552C 0.0316
uM
 48
hr
 3223 200 0.9616 0.9558 0.0621 0.0575 4