Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | C32 | 0.0032 | uM | 48 | hr | 2721 | 210 | 1.2218 | 1.1683 | 0.0772 | 0.0865 | 4 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 1962 | 179 | 0.7785 | 0.9919 | 0.0912 | 0.0829 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 2241 | 176 | 0.9016 | 0.9919 | 0.0785 | 0.0829 | 2 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 2977 | 256 | 1.1880 | 0.9919 | 0.0860 | 0.0829 | 3 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 2725 | 207 | 1.0994 | 0.9919 | 0.0760 | 0.0829 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 24 | hr | 2299 | 252 | 1.1835 | 1.1216 | 0.1096 | 0.1277 | 1 |
| AZ-628 | C32 | 0.0100 | uM | 24 | hr | 2199 | 325 | 1.0835 | 1.1216 | 0.1478 | 0.1277 | 2 |
| AZ-628 | C32 | 0.0100 | uM | 24 | hr | 2168 | 256 | 1.1054 | 1.1216 | 0.1181 | 0.1277 | 3 |
| AZ-628 | C32 | 0.0100 | uM | 24 | hr | 2228 | 301 | 1.1141 | 1.1216 | 0.1351 | 0.1277 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 2389 | 230 | 1.0505 | 1.1445 | 0.0963 | 0.1033 | 1 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 2205 | 279 | 0.9371 | 1.1445 | 0.1265 | 0.1033 | 2 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 3067 | 264 | 1.3639 | 1.1445 | 0.0861 | 0.1033 | 3 |
| AZ-628 | C32 | 0.0100 | uM | 48 | hr | 2815 | 294 | 1.2267 | 1.1445 | 0.1044 | 0.1033 | 4 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2395 | 157 | 0.9771 | 1.0955 | 0.0656 | 0.0581 | 1 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2623 | 141 | 1.0837 | 1.0955 | 0.0538 | 0.0581 | 2 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2925 | 134 | 1.2186 | 1.0955 | 0.0458 | 0.0581 | 3 |
| AZ-628 | C32 | 0.0100 | uM | 72 | hr | 2708 | 182 | 1.1029 | 1.0955 | 0.0672 | 0.0581 | 4 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 2275 | 387 | 1.0916 | 1.0452 | 0.1701 | 0.1770 | 1 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 1858 | 443 | 0.8181 | 1.0452 | 0.2384 | 0.1770 | 2 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 2345 | 340 | 1.1592 | 1.0452 | 0.1450 | 0.1770 | 3 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 2274 | 351 | 1.1118 | 1.0452 | 0.1544 | 0.1770 | 4 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2095 | 191 | 0.9264 | 1.0132 | 0.0912 | 0.0851 | 1 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2092 | 224 | 0.9089 | 1.0132 | 0.1071 | 0.0851 | 2 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2490 | 174 | 1.1269 | 1.0132 | 0.0699 | 0.0851 | 3 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2416 | 175 | 1.0904 | 1.0132 | 0.0724 | 0.0851 | 4 |