Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib MMAC-SF 3.1600
uM
 24
hr
 2924 167 1.0719 1.0600 0.0571 0.0615 3
Selumetinib MMAC-SF 3.1600
uM
 24
hr
 2886 190 1.0482 1.0600 0.0658 0.0615 4
Selumetinib MMAC-SF 3.1600
uM
 48
hr
 2620 560 0.5431 0.5325 0.2137 0.2315 1
Selumetinib MMAC-SF 3.1600
uM
 48
hr
 2607 516 0.5512 0.5325 0.1979 0.2315 2
Selumetinib MMAC-SF 3.1600
uM
 48
hr
 2840 761 0.5481 0.5325 0.2680 0.2315 3
Selumetinib MMAC-SF 3.1600
uM
 48
hr
 2455 605 0.4877 0.5325 0.2464 0.2315 4
Selumetinib MMAC-SF 3.1600
uM
 72
hr
 1143 638 0.1469 0.1414 0.5582 0.6168 1
Selumetinib MMAC-SF 3.1600
uM
 72
hr
 1255 743 0.1490 0.1414 0.5920 0.6168 2
Selumetinib MMAC-SF 3.1600
uM
 72
hr
 1276 842 0.1263 0.1414 0.6599 0.6168 3
Selumetinib MMAC-SF 3.1600
uM
 72
hr
 1438 945 0.1434 0.1414 0.6572 0.6168 4
Vemurafenib MMAC-SF 0.0032
uM
 24
hr
 1
Vemurafenib MMAC-SF 0.0032
uM
 24
hr
 2
Vemurafenib MMAC-SF 0.0032
uM
 24
hr
 2385 104 0.8868 0.9230 0.0436 0.0413 3
Vemurafenib MMAC-SF 0.0032
uM
 24
hr
 2567 100 0.9591 0.9230 0.0390 0.0413 4
Vemurafenib MMAC-SF 0.0032
uM
 48
hr
 3316 175 0.8280 0.9083 0.0528 0.0481 1
Vemurafenib MMAC-SF 0.0032
uM
 48
hr
 3591 153 0.9063 0.9083 0.0426 0.0481 2
Vemurafenib MMAC-SF 0.0032
uM
 48
hr
 3645 177 0.9143 0.9083 0.0486 0.0481 3
Vemurafenib MMAC-SF 0.0032
uM
 48
hr
 3924 190 0.9844 0.9083 0.0484 0.0481 4
Vemurafenib MMAC-SF 0.0032
uM
 72
hr
 3404 147 0.9475 0.9573 0.0432 0.0401 1
Vemurafenib MMAC-SF 0.0032
uM
 72
hr
 3335 112 0.9376 0.9573 0.0336 0.0401 2
Vemurafenib MMAC-SF 0.0032
uM
 72
hr
 3504 143 0.9778 0.9573 0.0408 0.0401 3
Vemurafenib MMAC-SF 0.0032
uM
 72
hr
 3470 149 0.9661 0.9573 0.0429 0.0401 4
Vemurafenib MMAC-SF 0.0100
uM
 24
hr
 1
Vemurafenib MMAC-SF 0.0100
uM
 24
hr
 2
Vemurafenib MMAC-SF 0.0100
uM
 24
hr
 2230 79 0.8363 0.8874 0.0354 0.0384 3