Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | LOXIMVI | 0.0100 | uM | 48 | hr | 2221 | 1.4125 | 1.5828 | 0.0540 | 0.0517 | 4 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 72 | hr | 3878 | 2.1774 | 1.9783 | 0.0678 | 0.1534 | 1 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 72 | hr | 3866 | 2.1834 | 1.9783 | 0.0623 | 0.1534 | 2 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 72 | hr | 1854 | 0.6595 | 1.9783 | 0.4094 | 0.1534 | 3 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 72 | hr | 5187 | 2.8929 | 1.9783 | 0.0740 | 0.1534 | 4 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 24 | hr | 2710 | 123 | 1.0564 | 0.9590 | 0.0454 | 0.0364 | 1 |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 24 | hr | 2911 | 101 | 1.1475 | 0.9590 | 0.0347 | 0.0364 | 2 |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 24 | hr | 2059 | 75 | 0.8102 | 0.9590 | 0.0364 | 0.0364 | 3 |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 24 | hr | 2073 | 60 | 0.8220 | 0.9590 | 0.0289 | 0.0364 | 4 |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 48 | hr | 2789 | 1.7870 | 1.6668 | 0.0470 | 0.0505 | 1 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 48 | hr | 2630 | 1.6815 | 1.6668 | 0.0490 | 0.0505 | 2 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 48 | hr | 2637 | 1.6747 | 1.6668 | 0.0554 | 0.0505 | 3 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 48 | hr | 2388 | 1.5241 | 1.6668 | 0.0507 | 0.0505 | 4 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 72 | hr | 3556 | 1.9581 | 2.3897 | 0.0858 | 0.0537 | 1 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 72 | hr | 4214 | 2.4400 | 2.3897 | 0.0387 | 0.0537 | 2 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 72 | hr | 4764 | 2.7442 | 2.3897 | 0.0437 | 0.0537 | 3 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 72 | hr | 4208 | 2.4165 | 2.3897 | 0.0466 | 0.0537 | 4 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 24 | hr | 2443 | 158 | 0.9331 | 0.9602 | 0.0647 | 0.0578 | 1 |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 24 | hr | 2932 | 162 | 1.1312 | 0.9602 | 0.0553 | 0.0578 | 2 |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 24 | hr | 2488 | 144 | 0.9572 | 0.9602 | 0.0579 | 0.0578 | 3 |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 24 | hr | 2119 | 113 | 0.8192 | 0.9602 | 0.0533 | 0.0578 | 4 |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 48 | hr | 2983 | 1.9201 | 1.8616 | 0.0426 | 0.0455 | 1 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 48 | hr | 2834 | 1.8233 | 1.8616 | 0.0430 | 0.0455 | 2 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 48 | hr | 3040 | 1.9484 | 1.8616 | 0.0467 | 0.0455 | 3 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 48 | hr | 2746 | 1.7547 | 1.8616 | 0.0495 | 0.0455 | 4 |