Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | LOXIMVI | 0.0032 | uM | 48 | hr | 1856 | 1.0905 | 0.9624 | 0.1261 | 0.1426 | 2 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 48 | hr | 1581 | 0.9870 | 0.9624 | 0.0715 | 0.1426 | 3 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 48 | hr | 1461 | 0.7194 | 0.9624 | 0.2676 | 0.1426 | 4 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 72 | hr | 2668 | 1.3245 | 1.2376 | 0.1758 | 0.2526 | 1 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 72 | hr | 2485 | 1.1854 | 1.2376 | 0.2081 | 0.2526 | 2 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 72 | hr | 2749 | 1.1811 | 1.2376 | 0.2867 | 0.2526 | 3 | |
| SB590885 | LOXIMVI | 0.0032 | uM | 72 | hr | 3167 | 1.2595 | 1.2376 | 0.3398 | 0.2526 | 4 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 24 | hr | 2809 | 88 | 1.1112 | 1.0089 | 0.0313 | 0.0390 | 1 |
| SB590885 | LOXIMVI | 0.0100 | uM | 24 | hr | 2965 | 178 | 1.1381 | 1.0089 | 0.0600 | 0.0390 | 2 |
| SB590885 | LOXIMVI | 0.0100 | uM | 24 | hr | 2310 | 83 | 0.9094 | 1.0089 | 0.0359 | 0.0390 | 3 |
| SB590885 | LOXIMVI | 0.0100 | uM | 24 | hr | 2210 | 63 | 0.8768 | 1.0089 | 0.0285 | 0.0390 | 4 |
| SB590885 | LOXIMVI | 0.0100 | uM | 48 | hr | 2391 | 1.4744 | 1.3982 | 0.0828 | 0.0806 | 1 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 48 | hr | 2480 | 1.5409 | 1.3982 | 0.0758 | 0.0806 | 2 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 48 | hr | 1968 | 1.2391 | 1.3982 | 0.0635 | 0.0806 | 3 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 48 | hr | 2213 | 1.3386 | 1.3982 | 0.1003 | 0.0806 | 4 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 72 | hr | 2406 | 1.2558 | 1.5053 | 0.1334 | 0.1880 | 1 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 72 | hr | 3128 | 1.5431 | 1.5053 | 0.1810 | 0.1880 | 2 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 72 | hr | 3323 | 1.6016 | 1.5053 | 0.1998 | 0.1880 | 3 | |
| SB590885 | LOXIMVI | 0.0100 | uM | 72 | hr | 3530 | 1.6208 | 1.5053 | 0.2377 | 0.1880 | 4 | |
| SB590885 | LOXIMVI | 0.0316 | uM | 24 | hr | 2888 | 116 | 1.1320 | 1.0209 | 0.0402 | 0.0361 | 1 |
| SB590885 | LOXIMVI | 0.0316 | uM | 24 | hr | 3151 | 128 | 1.2345 | 1.0209 | 0.0406 | 0.0361 | 2 |
| SB590885 | LOXIMVI | 0.0316 | uM | 24 | hr | 2161 | 51 | 0.8616 | 1.0209 | 0.0236 | 0.0361 | 3 |
| SB590885 | LOXIMVI | 0.0316 | uM | 24 | hr | 2182 | 87 | 0.8555 | 1.0209 | 0.0399 | 0.0361 | 4 |
| SB590885 | LOXIMVI | 0.0316 | uM | 48 | hr | 2993 | 1.8993 | 1.8514 | 0.0561 | 0.0671 | 1 | |
| SB590885 | LOXIMVI | 0.0316 | uM | 48 | hr | 3115 | 1.9470 | 1.8514 | 0.0703 | 0.0671 | 2 |