Metrics for growth responses of MDA-MB-231 and HME-1 cell lines to LINCS Pilot Phase TransCenter Project kinase inhibitors - Dataset (ID:20216)

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Small Molecule Cell Line IC50 GI50 EC50 Hill Slope E_inf Experiment Date
Pictilisib HME1 6.455 4.322 4.128 2.843 0.647
2014-03-19
Pictilisib HME1 3.718 2.617 2.792 2.028 0.792
2014-04-01
Pictilisib HME1 2.627 1.920 1.911 2.213 0.760
2014-04-08
MK2206 HME1 15.715 10.409 15.466 1.508 1.000
2014-03-19
MK2206 HME1 8.201 5.356 8.237 1.450 0.980
2014-04-01
MK2206 HME1 5.751 3.782 5.769 1.281 1.000
2014-04-08
PD0325901 HME1 0.053 3.263 0.300
2014-03-19
PD0325901 HME1 0.037 0.021 0.017 2.016 0.608
2014-04-01
PD0325901 HME1 0.038 0.024 0.019 3.504 0.552
2014-04-08
Torin1 HME1 0.016 2.603 0.213
2014-03-19
Torin1 HME1 0.016 0.010 2.769 0.458
2014-04-01
Torin1 HME1 0.016 0.010 2.614 0.476
2014-04-08
WYE-125132 HME1 0.100 2.814 0.264
2014-03-19
WYE-125132 HME1 0.161 0.086 0.071 1.761 0.621
2014-04-01
WYE-125132 HME1 0.257 0.092 0.063 2.475 0.516
2014-04-08
Pictilisib MDA-MB-231 15.122 9.425 15.828 1.124 1.000
2014-03-19
Pictilisib MDA-MB-231 10.160 4.012 11.000 0.646 1.000
2014-04-01
Pictilisib MDA-MB-231 8.918 2.892 8.819 0.596 1.000
2014-04-08
MK2206 MDA-MB-231 20.056 18.447 20.026 4.000 1.000
2014-03-19
MK2206 MDA-MB-231 13.251 11.242 13.225 4.000 0.971
2014-04-01
MK2206 MDA-MB-231 14.385 11.918 14.570 4.000 1.000
2014-04-08
PD0325901 MDA-MB-231 0.123 0.034 0.023 0.687 0.665
2014-03-19
PD0325901 MDA-MB-231 0.200 0.048 0.029 0.923 0.589
2014-04-01
PD0325901 MDA-MB-231 0.149 0.035 0.039 0.691 0.709
2014-04-08
Torin1 MDA-MB-231 0.426 0.092 0.048 1.215 0.536
2014-03-19
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