VX-680 KINOMEscan - Dataset (ID:20197)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Tozasertib | AAK1 | 290.0 | nM |
| Tozasertib | ABL1(E255K)-phosphorylated | 3.0 | nM |
| Tozasertib | ABL1(F317I)-nonphosphorylated | 7200.0 | nM |
| Tozasertib | ABL1(F317I)-phosphorylated | 2100.0 | nM |
| Tozasertib | ABL1(F317L)-nonphosphorylated | 480.0 | nM |
| Tozasertib | ABL1(F317L)-phosphorylated | 400.0 | nM |
| Tozasertib | ABL1(H396P)-nonphosphorylated | 3.3 | nM |
| Tozasertib | ABL1(H396P)-phosphorylated | 3.1 | nM |
| Tozasertib | ABL1(M351T)-phosphorylated | 5.3 | nM |
| Tozasertib | ABL1(Q252H)-nonphosphorylated | 3.8 | nM |
| Tozasertib | ABL1(Q252H)-phosphorylated | 9.4 | nM |
| Tozasertib | ABL1(T315I)-nonphosphorylated | 9.7 | nM |
| Tozasertib | ABL1(T315I)-phosphorylated | 9.3 | nM |
| Tozasertib | ABL1(Y253F)-phosphorylated | 7.8 | nM |
| Tozasertib | ABL1-nonphosphorylated | 13.0 | nM |
| Tozasertib | ABL1-phosphorylated | 7.5 | nM |
| Tozasertib | ABL2 | 4.0 | nM |
| Tozasertib | ACVR1 | 1900.0 | nM |
| Tozasertib | ACVR1B | nM | |
| Tozasertib | ACVR2A | nM | |
| Tozasertib | ACVR2B | nM | |
| Tozasertib | ACVRL1 | 9500.0 | nM |
| Tozasertib | ADCK3 | nM | |
| Tozasertib | ADCK4 | nM | |
| Tozasertib | AKT1 | nM |