TG-101348 KINOMEscan - Dataset (ID:20174)
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| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Fedratinib | AAK1 | 35.0 | nM |
| Fedratinib | ABL1(E255K)-phosphorylated | 40.0 | nM |
| Fedratinib | ABL1(F317I)-nonphosphorylated | 2100.0 | nM |
| Fedratinib | ABL1(F317I)-phosphorylated | 560.0 | nM |
| Fedratinib | ABL1(F317L)-nonphosphorylated | 450.0 | nM |
| Fedratinib | ABL1(F317L)-phosphorylated | 180.0 | nM |
| Fedratinib | ABL1(H396P)-nonphosphorylated | 45.0 | nM |
| Fedratinib | ABL1(H396P)-phosphorylated | 61.0 | nM |
| Fedratinib | ABL1(M351T)-phosphorylated | 50.0 | nM |
| Fedratinib | ABL1(Q252H)-nonphosphorylated | 110.0 | nM |
| Fedratinib | ABL1(Q252H)-phosphorylated | 54.0 | nM |
| Fedratinib | ABL1(T315I)-nonphosphorylated | 240.0 | nM |
| Fedratinib | ABL1(T315I)-phosphorylated | 65.0 | nM |
| Fedratinib | ABL1(Y253F)-phosphorylated | 56.0 | nM |
| Fedratinib | ABL1-nonphosphorylated | 180.0 | nM |
| Fedratinib | ABL1-phosphorylated | 44.0 | nM |
| Fedratinib | ABL2 | 570.0 | nM |
| Fedratinib | ACVR1 | 150.0 | nM |
| Fedratinib | ACVR1B | 6700.0 | nM |
| Fedratinib | ACVR2A | nM | |
| Fedratinib | ACVR2B | nM | |
| Fedratinib | ACVRL1 | 2400.0 | nM |
| Fedratinib | ADCK3 | 7000.0 | nM |
| Fedratinib | ADCK4 | 300.0 | nM |
| Fedratinib | AKT1 | nM |