Nilotinib KINOMEscan - Dataset (ID:20162)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200327 | PIK3CA(E545K) | 200327 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545K | Mutation (E545K); Partial length | ||
| 200329 | PIK3CA(H1047Y) | 200329 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047Y | Mutation (H1047Y); Partial length | ||
| 200331 | PIK3CA(M1043I) | 200331 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | M1043I | Mutation (M1043I); Partial length | ||
| 200332 | PIK3CA(Q546K) | 200332 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Q546K | Mutation (Q546K); Partial length | ||
| 200323 | PIK3CA | 200323 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Wild Type; Partial length | |||
| 200324 | PIK3CA(C420R) | 200324 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | C420R | Mutation (C420R); Partial length | ||
| 200325 | PIK3CA(E542K) | 200325 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E542K | Mutation (E542K); Partial length | ||
| 200333 | PIK3CB | 200333 | P42338 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; DKFZp779K1237; MGC133043; P110BETA; PI3K; PI3KBETA; PIK3C1; PIK3CB; PI3K-beta | KINOMEscan | Wild Type; Partial length | |||
| 200277 | MTOR | 200277 | P42345 | Mechanistic target of rapamycin (serine/threonine kinase); FLJ44809; FRAP; FRAP1; FRAP2; MTOR; RAFT1; RAPT1 | KINOMEscan | Wild Type; Partial length | |||
| 200105 | CTK | 200105 | P42679 | Megakaryocyte-associated tyrosine kinase; CHK; CTK; DKFZp434N1212; HHYLTK; HYL; HYLTK; Lsk; MATK; MGC1708; MGC2101 | KINOMEscan | Wild Type; Full length | |||
| 200431 | TEC | 200431 | P42680 | Tyrosine-protein kinase Tec; MGC126760; MGC126762; PSCTK4; TEC | KINOMEscan | Wild Type; Partial length | |||
| 200449 | TXK | 200449 | P42681 | TXK tyrosine kinase; BTKL; MGC22473; PSCTK5; PTK4; RLK; TKL; TXK | KINOMEscan | Wild Type; Partial length | |||
| 200026 | ABL2 | 200026 | P42684 | V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene); ABL2; ABLL; ARG; FLJ22224; FLJ31718; FLJ41441 | KINOMEscan | Wild Type; Partial length | |||
| 200176 | FRK | 200176 | P42685 | Tyrosine-protein kinase FRK; Fyn-related kinase; FRK; GTK; PTK5; RAK | KINOMEscan | Wild Type; Partial length | |||
| 200469 | ZAP70 | 200469 | P43403 | Tyrosine-protein kinase ZAP-70; Zeta-chain (TCR) associated protein kinase 70kDa; FLJ17670; FLJ17679; SRK; STD; TZK; ZAP70; ZAP-70 | KINOMEscan | Wild Type; Partial length | |||
| 200425 | SYK | 200425 | P43405 | Tyrosine-protein kinase SYK; spleen tyrosine kinase; p72-Syk; DKFZp313N1010; FLJ25043; FLJ37489; SYK | KINOMEscan | Wild Type; Partial length | |||
| 200211 | JNK1 | 200211 | P45983 | Mitogen-activated protein kinase 8; JNK; JNK1; JNK1A2; JNK21B1/2; MAPK8; PRKM8; SAPK1 | KINOMEscan | Wild Type; Full length | |||
| 200212 | MK09 | 200212 | P45984 | Mitogen-activated protein kinase 9; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; MAPK9; p54a; p54aSAPK; PRKM9; SAPK | KINOMEscan | Wild Type; Full length | |||
| 200254 | MP2K4 | 200254 | P45985 | Dual specificity mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4; JNKK; JNKK1; MAP2K4; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SEK1/MAP2K4; SERK1 | KINOMEscan | Wild Type; Partial length | |||
| 200253 | MP2K3 | 200253 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 3; MAP2K3; MAPKK3; MEK3; MKK3; MKK3/MAP2K3; PRKMK3 | KINOMEscan | Wild Type; Full length | |||
| 200096 | CSNK1A1 | 200096 | P48729 | Casein kinase 1, alpha 1; CK1; CK1a; CSNK1A1; HLCDGP1; PRO2975 | KINOMEscan | Wild Type; Partial length | |||
| 200098 | CSNK1D | 200098 | P48730 | Casein kinase 1, delta; CK1d; CSNK1D; HCKID | KINOMEscan | Wild Type; Full length | |||
| 200335 | PIK3CG | 200335 | P48736 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; PI3CG; PI3K; PI3Kgamma; PIK3; PIK3CG | KINOMEscan | Wild Type; Partial length | |||
| 200244 | MAPKAPK2 | 200244 | P49137 | Mitogen-activated protein kinase-activated protein kinase 2; MAPKAPK2; MK2 | KINOMEscan | Wild Type; Partial length | |||
| 200081 | CDK8 | 200081 | P49336 | Cyclin-dependent kinase 8; cell division protein kinase 8; CDK8; K35; MGC126074; MGC126075 | KINOMEscan | Wild Type; Partial length |