Nilotinib KINOMEscan - Dataset (ID:20162)
Proteins Studied
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200148 | ERBB2 | 200148 | P04626 | Receptor tyrosine-protein kinase erbB-2; CD340; ERBB2; HER2; HER-2; HER-2/neu; MLN 19; NEU; NGL; TKR1 | KINOMEscan | Wild Type; Partial length | |||
200443 | TRKA | 200443 | P04629 | Neurotrophic tyrosine kinase, receptor, type 1; DKFZp781I14186; MTC; NTRK1; p140-TrkA; TRK; TRK1; TRKA; Trk-A | KINOMEscan | Wild Type; Partial length | |||
200197 | INSR | 200197 | P06213 | Insulin receptor; CD220; HHF5; INSR; IR | KINOMEscan | Wild Type; Partial length | |||
200224 | LCK | 200224 | P06239 | Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16 | KINOMEscan | Wild Type; Partial length | |||
200177 | FYN | 200177 | P06241 | FYN oncogene related to SRC, FGR, YES; FYN; MGC45350; SLK; SYN | KINOMEscan | Wild Type; Partial length | |||
200160 | FES | 200160 | P07332 | Feline sarcoma oncogene; FES; FPS | KINOMEscan | Wild Type; Partial length | |||
200094 | CSF1R | 200094 | P07333 | Colony stimulating factor 1 receptor; CD115; C-FMS; CSF1R; CSF-1R; CSF-1-R; CSFR; FIM2; FIM-2; FMS; Fms/CSFR | KINOMEscan | Wild Type; Partial length | |||
200465 | YES | 200465 | P07947 | Tyrosine-protein kinase Yes; Proto-oncogene tyrosine-protein kinase Yes | KINOMEscan | Wild Type; Partial length | |||
200232 | LYN | 200232 | P07948 | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; FLJ26625; JTK8; LYN | KINOMEscan | Wild Type; Partial length | |||
200371 | RET(M918T) | 200371 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | M918T | Mutation (M918T); Partial length | ||
200373 | RET(V804M) | 200373 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804M | Mutation (V804M); Partial length | ||
200372 | RET(V804L) | 200372 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804L | Mutation (V804L); Partial length | ||
200370 | RET | 200370 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | Wild Type; Partial length | |||
200193 | IGF1R | 200193 | P08069 | Insulin-like growth factor 1 receptor; CD221; IGF1R; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216 | KINOMEscan | Wild Type; Partial length | |||
200261 | MET(Y1235D) | 200261 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | Y1235D | Mutation (Y1235D); Partial length | ||
200259 | MET | 200259 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | Wild Type; Partial length | |||
200260 | MET(M1250T) | 200260 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | M1250T | Mutation (M1250T); Partial length | ||
200185 | HCK | 200185 | P08631 | Hemopoietic cell kinase; HCK; JTK9 | KINOMEscan | Wild Type; Full length | |||
200383 | ROS1 | 200383 | P08922 | C-ros oncogene 1 , receptor tyrosine kinase; c-ros-1; MCF3; ROS; ROS1 | KINOMEscan | Wild Type; Partial length | |||
200313 | PGFRB | 200313 | P09619 | Platelet-derived growth factor receptor, beta polypeptide; CD140B; JTK12; PDGFR; PDGFR1; PDGFRB; PDGFR-b; PDGFRbeta; PEGFR-beta | KINOMEscan | Wild Type; Partial length | |||
200166 | FGR | 200166 | P09769 | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; c-fgr; c-src2; FGR; FLJ43153; MGC75096; p55c-fgr; p55-Fgr; p58c-fgr; SRC2 | KINOMEscan | Wild Type; Partial length | |||
200349 | PKNB(M.tuberculosis) | 200349 | P0A5S4 | Transmembrane Serine/Threonine-Protein Kinase B; PKNB; Protein Kinase B; STPK B | KINOMEscan | Wild Type; Partial length | |||
200461 | WEE2 | 200461 | P0C1S8 | Wee1-like protein kinase 2; FLJ16107; WEE1B; WEE2 | KINOMEscan | Wild Type; Partial length | |||
200408 | SgK110 | 200408 | P0C264 | Putative uncharacterized serine/threonine-protein kinase (Sugen kinase 110); SgK110 | KINOMEscan | Wild Type; Partial length | |||
200214 | KIT | 200214 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | Wild Type; Partial length |