Nilotinib KINOMEscan - Dataset (ID:20162)
Proteins Studied
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200207 | JAK2(JH1domain-catalytic) | 200207 | O60674 | Janus kinase 2; JAK2; JAK2-catalytic; JTK10 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
| 200382 | ROCK2 | 200382 | O75116 | Rho-associated protein kinase 2; Rho-associated, coiled-coil containing protein kinase 2; KIAA0619; ROCK2 | KINOMEscan | Wild Type; Partial length | |||
| 200455 | ULK1 | 200455 | O75385 | Serine/threonine-protein kinase ULK1; Unc-51-like kinase 1 (C. elegans); ATG1; FLJ38455; FLJ46475; ULK1; UNC51; Unc51.1 | KINOMEscan | Wild Type; Partial length | |||
| 200157 | ERN1 | 200157 | O75460 | Endoplasmic reticulum to nucleus signaling 1; ERN1; FLJ30999; hIRE1p; IRE1; IRE1a; IRE1P; MGC163277; MGC163279 | KINOMEscan | Wild Type; Partial length | |||
| 200396 | RPS6KA5(Kin.Dom.2-C-terminal) | 200396 | O75582 | Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSK1~b; MSPK1; RLPK; RPS6KA5 | KINOMEscan | Kin.Dom.2-C-terminal | Wild Type; Partial length | ||
| 200394 | RPS6KA5(Kin.Dom.1-N-terminal) | 200394 | O75582 | Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSPK1; RLPK; RPS6KA5 | KINOMEscan | Kin.Dom.1-N-terminal | Wild Type; Partial length | ||
| 200390 | RPS6KA4(Kin.Dom.1-N-terminal) | 200390 | O75676 | Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; RPS6KA4; RSK-B | KINOMEscan | Kin.Dom.1-N-terminal | Wild Type; Partial length | ||
| 200392 | RPS6KA4(Kin.Dom.2-C-terminal) | 200392 | O75676 | Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; MSK2~b; RPS6KA4; RSK-B | KINOMEscan | Kin.Dom.2-C-terminal | Wild Type; Partial length | ||
| 200420 | STK16 | 200420 | O75716 | Serine/threonine kinase 16; FLJ39635; KRCT; MGC16211; MPSK; MPSK1; PKL12; STK16; TSF1 | KINOMEscan | Wild Type; Partial length | |||
| 200322 | PIK3C2G | 200322 | O75747 | Phosphoinositide-3-kinase, class 2, gamma polypeptide; MGC163149; PI3K-C2GAMMA; PIK3C2G | KINOMEscan | Wild Type; Partial length | |||
| 200304 | PAK3 | 200304 | O75914 | P21 protein (Cdc42/Rac)-activated kinase 3; bPAK; CDKN1A; hPAK3; MRX30; MRX47; OPHN3; PAK3; PAK3beta | KINOMEscan | Wild Type; Full length | |||
| 200086 | CDKL5 | 200086 | O76039 | Cyclin-dependent kinase-like 5; CDKL5; ISSX; STK9 | KINOMEscan | Wild Type; Partial length | |||
| 200118 | DRAK2 | 200118 | O94768 | Serine/threonine kinase 17b; DRAK2; STK17B | KINOMEscan | Wild Type; Full length | |||
| 200228 | LOK | 200228 | O94804 | Serine/threonine-protein kinase 10 | KINOMEscan | Wild Type; Partial length | |||
| 200361 | KPCD3 | 200361 | O94806 | Protein kinase D3; EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN; PRKD3 | KINOMEscan | Wild Type; Partial length | |||
| 200318 | CDK14 | 200318 | O94921 | Cyclin-dependent kinase 14; serine/threonine-protein kinase PFTAIRE-1; PFTK1 | KINOMEscan | Wild Type; Full length | |||
| 200043 | M3K6 | 200043 | O95382 | Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114 | KINOMEscan | Wild Type; Partial length | |||
| 200297 | OSR1 | 200297 | O95747 | Serine/threonine-protein kinase OSR1; oxidative-stress responsive 1; KIAA1101; OSR1; OXSR1 | KINOMEscan | Wild Type; Full length | |||
| 200242 | MAP4K4 | 200242 | O95819 | Mitogen-activated protein kinase kinase kinase kinase 4; FLH21957; FLJ10410; FLJ20373; FLJ90111; HGK; HGK/ZC1; KIAA0687; MAP4K4; NIK; ZC1 | KINOMEscan | Wild Type; Partial length | |||
| 200222 | LATS1 | 200222 | O95835 | LATS, large tumor suppressor, homolog 1 (Drosophila); LATS1; WARTS; wts | KINOMEscan | Wild Type; Partial length | |||
| 200305 | PAK4 | 200305 | O96013 | P21 protein (Cdc42/Rac)-activated kinase 4; PAK4 | KINOMEscan | Wild Type; Partial length | |||
| 200088 | CHK2 | 200088 | O96017 | Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog | KINOMEscan | Wild Type; Partial length | |||
| 200024 | ABL1-nonphosphorylated | 200024 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | nonphosphorylated | Wild Type; Partial length | ||
| 200012 | ABL1(H396P)-nonphosphorylated | 200012 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | nonphosphorylated | Mutation (H396P); Partial length | |
| 200023 | ABL1(Y253F)-phosphorylated | 200023 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | phosphorylated | Mutation (Y253F); Partial length |