CI-1040 KINOMEscan - Dataset (ID:20153)
Proteins Studied
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200209 | JAK3(JH1domain-catalytic) | 200209 | P52333 | Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; L-JAK | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200450 | TYK2(JH1domain-catalytic) | 200450 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200203 | JAK1(JH1domain-catalytic) | 200203 | P23458 | Janus kinase 1; JAK1; JAK1A; JAK1B; JAK1-catalytic; JTK3 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200207 | JAK2(JH1domain-catalytic) | 200207 | O60674 | Janus kinase 2; JAK2; JAK2-catalytic; JTK10 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200451 | TYK2(JH2domain-pseudokinase) | 200451 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH2domain-pseudokinase | Wild Type; Partial length | ||
200204 | JAK1(JH2domain-pseudokinase) | 200204 | P23458 | Janus kinase 1; JAK1; JAK1~b; JAK1A; JAK1B; JAK1-pseudokinase; JTK3 | KINOMEscan | JH2domain-pseudokinase | Wild Type; Partial length | ||
200394 | RPS6KA5(Kin.Dom.1-N-terminal) | 200394 | O75582 | Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSPK1; RLPK; RPS6KA5 | KINOMEscan | Kin.Dom.1-N-terminal | Wild Type; Partial length | ||
200390 | RPS6KA4(Kin.Dom.1-N-terminal) | 200390 | O75676 | Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; RPS6KA4; RSK-B | KINOMEscan | Kin.Dom.1-N-terminal | Wild Type; Partial length | ||
200401 | RSK2(Kin.Dom.1-N-terminal) | 200401 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
200399 | RSK1(Kin.Dom.1-N-terminal) | 200399 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
200404 | RSK4(Kin.Dom.1-N-terminal) | 200404 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
200402 | RSK3(Kin.Dom.1-N-terminal) | 200402 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90RSK; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1/p90RSK; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
200179 | GCN2(Kin.Dom.2,S808G) | 200179 | Q9P2K8 | Eukaryotic translation initiation factor 2 alpha kinase 4; EIF2AK4; GCN2; KIAA1338 | KINOMEscan | S808G | Kin.Dom.2 | Wild Type; Partial length | |
200396 | RPS6KA5(Kin.Dom.2-C-terminal) | 200396 | O75582 | Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSK1~b; MSPK1; RLPK; RPS6KA5 | KINOMEscan | Kin.Dom.2-C-terminal | Wild Type; Partial length | ||
200392 | RPS6KA4(Kin.Dom.2-C-terminal) | 200392 | O75676 | Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; MSK2~b; RPS6KA4; RSK-B | KINOMEscan | Kin.Dom.2-C-terminal | Wild Type; Partial length | ||
200405 | RSK4(Kin.Dom.2-C-terminal) | 200405 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
200400 | RSK1(Kin.Dom.2-C-terminal) | 200400 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
200403 | RSK3(Kin.Dom.2-C-terminal) | 200403 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1~b; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
200024 | ABL1-nonphosphorylated | 200024 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | nonphosphorylated | Wild Type; Partial length | ||
200023 | ABL1(Y253F)-phosphorylated | 200023 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | phosphorylated | Mutation (Y253F); Partial length | |
200012 | ABL1(H396P)-nonphosphorylated | 200012 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | nonphosphorylated | Mutation (H396P); Partial length | |
200021 | ABL1(T315I)-phosphorylated | 200021 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | phosphorylated | Mutation (T315I); Partial length | |
200033 | ADCK4 | 200033 | Q96D53 | AarF domain containing kinase 4; ADCK4; FLJ12229 | KINOMEscan | Wild Type; Full length | |||
200020 | ABL1(T315I)-nonphosphorylated | 200020 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | nonphosphorylated | Mutation (T315I); Partial length | |
200010 | ABL1(F317L)-phosphorylated | 200010 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | phosphorylated | Mutation (F317L); Partial length |