AMG-706 KINOMEscan - Dataset (ID:20150)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Motesanib | LCK | 360.0 | nM |
| Motesanib | KIT(D816V) | 410.0 | nM |
| Motesanib | EPHA6 | 490.0 | nM |
| Motesanib | BRAF | 630.0 | nM |
| Motesanib | ABL1(Q252H)-nonphosphorylated | 670.0 | nM |
| Motesanib | ABL1-nonphosphorylated | 680.0 | nM |
| Motesanib | RAF1 | 880.0 | nM |
| Motesanib | ABL1(F317L)-nonphosphorylated | 910.0 | nM |
| Motesanib | EGFR(L747-E749del, A750P) | 960.0 | nM |
| Motesanib | PTK6 | 1000.0 | nM |
| Motesanib | FLT3(ITD) | 1000.0 | nM |
| Motesanib | EGFR(G719S) | 1000.0 | nM |
| Motesanib | FLT3(N841I) | 1100.0 | nM |
| Motesanib | LOK | 1100.0 | nM |
| Motesanib | TAK1 | 1300.0 | nM |
| Motesanib | SLK | 1300.0 | nM |
| Motesanib | EGFR | 1300.0 | nM |
| Motesanib | ABL1(H396P)-nonphosphorylated | 1400.0 | nM |
| Motesanib | AURKC | 1900.0 | nM |
| Motesanib | MAP3K3 | 2100.0 | nM |
| Motesanib | BLK | 2200.0 | nM |
| Motesanib | EGFR(G719C) | 2300.0 | nM |
| Motesanib | EGFR(L747-T751del,Sins) | 2600.0 | nM |
| Motesanib | FYN | 2800.0 | nM |
| Motesanib | FLT3(R834Q) | 3800.0 | nM |