Dabrafenib KINOMEscan - Dataset (ID:20131)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200117 | DRAK1 | 200117 | Q9UEE5 | Serine/threonine kinase 17a; DRAK1; STK17A | KINOMEscan | Wild Type; Partial length | |||
| 200424 | STK39 | 200424 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); DCHT; DKFZp686K05124; PASK; SPAK; STLK3 | KINOMEscan | Wild Type; Partial length | |||
| 200140 | EPHA6 | 200140 | Q9UF33 | EPH receptor A6; DKFZp434C1418; EPA6; EPHA6; FLJ35246; PRO57066 | KINOMEscan | Wild Type; Partial length | |||
| 200430 | TBK1 | 200430 | Q9UHD2 | Serine/threonine-protein kinase TBK1; TANK-binding kinase 1; NF-kappa-B-activating kinase; FLJ11330; NAK; T2K; TBK1 | KINOMEscan | Wild Type; Full length | |||
| 200107 | DAPK2 | 200107 | Q9UIK4 | Death-associated protein kinase 2; DAPK2; DRP1; DRP-1; MGC119312 | KINOMEscan | Wild Type; Full length | |||
| 200404 | RSK4(Kin.Dom.1-N-terminal) | 200404 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
| 200405 | RSK4(Kin.Dom.2-C-terminal) | 200405 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
| 200439 | TNIK | 200439 | Q9UKE5 | TRAF2 and NCK interacting kinase; TNIK; TNIK/ZC2; ZC2 | KINOMEscan | Wild Type; Partial length | |||
| 200437 | TLK1 | 200437 | Q9UKI8 | Serine/threonine-protein kinase tousled-like 1; tousled-like kinase 1; KIAA0137; PKU-beta; TLK1 | KINOMEscan | Wild Type; Partial length | |||
| 200428 | TAOK2 | 200428 | Q9UL54 | Serine/threonine-protein kinase TAO2; prostate-derived sterile 20-like kinase 1; hKFC-C; KIAA0881; MAP3K17; PSK; PSK1; PSK1-BETA; TAO2; TAOK2 | KINOMEscan | Wild Type; Partial length | |||
| 200037 | ALK | 200037 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | Wild Type; Partial length | |||
| 200480 | ALK(L1196M) | 200480 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | L1196M | |||
| 200479 | ALK(C1156Y) | 200479 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | C1156Y | |||
| 200419 | SRPK3 | 200419 | Q9UPE1 | SFRS protein kinase 3; MGC102944; MSSK1; SRPK3; STK23 | KINOMEscan | Wild Type; Partial length | |||
| 200192 | ICK | 200192 | Q9UPZ9 | Intestinal cell (MAK-like) kinase; ECO; ICK; KIAA0936; LCK2; MGC46090; MRK | KINOMEscan | Wild Type; Partial length | |||
| 200072 | CDC2L2 | 200072 | Q9UQ88 | Cyclin-dependent kinase 11A; CDC2L2; CDC2L3; CDK11A; CDK11-p110; CDK11-p46; CDK11-p58; MGC131975; p58GTA; PITSLRE | KINOMEscan | Wild Type; Partial length | |||
| 200046 | AURKC | 200046 | Q9UQB9 | Aurora kinase C; AIE2; AIK3; ARK3; Aur3; AurC; AurC/Aur3; AURKC; aurora-C; STK13 | KINOMEscan | Wild Type; Full length | |||
| 200063 | CAMK2A | 200063 | Q9UQM7 | Calcium/calmodulin-dependent protein kinase II alpha; CAMK2A; CAMKA; KIAA0968 | KINOMEscan | Wild Type; Partial length | |||
| 200036 | AKT3 | 200036 | Q9Y243 | V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); AKT3; Akt3/PKBg; DKFZp434N0250; PKBg; PKB-GAMMA; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2 | KINOMEscan | Wild Type; Partial length | |||
| 200285 | NDR2 | 200285 | Q9Y2H1 | Serine/threonine kinase 38 like; KIAA0965; NDR2; STK38L | KINOMEscan | Wild Type; Partial length | |||
| 200250 | MAST1 | 200250 | Q9Y2H9 | Microtubule associated serine/threonine kinase 1; KIAA0973; MAST1; SAST; SAST170 | KINOMEscan | Wild Type; Partial length | |||
| 200368 | SIK3 | 200368 | Q9Y2K2 | Serine/threonine-protein kinase SIK3; SIK family kinase 3; FLJ12240; KIAA0999; L19; QSK | KINOMEscan | Wild Type; Partial length | |||
| 200237 | M3K2 | 200237 | Q9Y2U5 | Mitogen-activated protein kinase kinase kinase 2; MAP3K2; MEKK2; MEKK2/MAP3K2; MEKK2B | KINOMEscan | Wild Type; Partial length | |||
| 200120 | DYRK1B | 200120 | Q9Y463 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; MIRK | KINOMEscan | Wild Type; Full length | |||
| 200243 | MAP4K5 | 200243 | Q9Y4K4 | Mitogen-activated protein kinase kinase kinase kinase 5; GCKR; KHS; KHS1; MAP4K5; MAPKKKK5 | KINOMEscan | Wild Type; Partial length |