Dabrafenib KINOMEscan - Dataset (ID:20131)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200363 KGP2 200363 Q13237
Protein kinase, cGMP-dependent, type II; cGKII; PKG2; PRKG2; PRKGR2
KINOMEscan Wild Type; Partial length
200214 KIT 200214 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan Wild Type; Partial length
200215 KIT(A829P) 200215 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan A829P Mutation (A829P); Partial length
200474 KIT-autoinhibited 200474 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan
200216 KIT(D816H) 200216 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan D816H Mutation (D816H); Partial length
200217 KIT(D816V) 200217 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan D816V Mutation (D816V); Partial length
200218 KIT(L576P) 200218 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan L576P Mutation (L576P); Partial length
200219 KIT(V559D) 200219 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D Mutation (V559D); Partial length
200220 KIT(V559D,T670I) 200220 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D,T670I Mutation (V559D,T670I); Partial length
200221 KIT(V559D,V654A) 200221 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D,V654A Mutation (V559D,V654A); Partial length
200068 KKCC1 200068 Q8N5S9
Calcium/calmodulin-dependent protein kinase kinase 1, CaM-kinase IV kinase; CAMKK1; CAMKKA; DKFZp761M0423; MGC34095
KINOMEscan Wild Type; Partial length
200354 KPCD 200354 Q05655
Protein kinase C, delta; May1; MGC49908; nPKC-delta; PKCD; PRKCD
KINOMEscan Wild Type; Partial length
200359 KPCD1 200359 Q15139
Protein kinase D1; PKCM; PKC-MU; PKD; PKD1; PRKCM; PRKD1
KINOMEscan Wild Type; Partial length
200360 KPCD2 200360 Q9BZL6
Protein kinase D2; HSPC187; PKD2; PRKD2
KINOMEscan Wild Type; Partial length
200361 KPCD3 200361 O94806
Protein kinase D3; EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN; PRKD3
KINOMEscan Wild Type; Partial length
200355 KPCE 200355 Q02156
Protein kinase C, epsilon; MGC125656; MGC125657; nPKC-epsilon; PKCE; PRKCE
KINOMEscan Wild Type; Partial length
200357 KPCI 200357 P41743
Protein kinase C, iota; DXS1179E; MGC26534; nPKC-iota; PKCI; PRKCI
KINOMEscan Wild Type; Partial length
200356 KPCL 200356 P24723
Protein kinase C, eta; MGC26269; MGC5363; nPKC-eta; PKCL; PKC-L; PRKCH; PRKCL
KINOMEscan Wild Type; Partial length
200358 KPCT 200358 Q04759
Protein kinase C theta type; MGC126514; MGC141919; nPKC-theta; PKCt; PRKCQ; PRKCT
KINOMEscan Wild Type; Partial length
200222 LATS1 200222 O95835
LATS, large tumor suppressor, homolog 1 (Drosophila); LATS1; WARTS; wts
KINOMEscan Wild Type; Partial length
200223 LATS2 200223 Q9NRM7
LATS, large tumor suppressor, homolog 2 (Drosophila); FLJ13161; KPM; LATS2
KINOMEscan Wild Type; Partial length
200224 LCK 200224 P06239
Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16
KINOMEscan Wild Type; Partial length
200225 LIMK1 200225 P53667
LIM domain kinase 1; LIMK
KINOMEscan Wild Type; Full length
200226 LIMK2 200226 P53671
LIM domain kinase 2; LIMK2
KINOMEscan Wild Type; Full length
200227 LKB1 200227 Q15831
Serine/threonine kinase 11; LKB1; PJS; STK11
KINOMEscan Wild Type; Full length